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用来自另一家机构的额外数据集更新“口咽鳞状细胞癌患者个体淋巴结受累情况数据集”。

Updating "A dataset on patient-individual lymph node involvement in oropharyngeal squamous cell carcinoma" with an additional dataset from a second institution.

作者信息

Benavente Sergi, Ludwig Roman, Balermpas Panagiotis, Unkelbach Jan

机构信息

Department of Radiation Oncology, Vall d'Hebron University Hospital, Pg. de la Vall d'Hebron 119, 08035 Barcelona (ES), Spain.

Departement of Radiation Oncology, University Hospital Zurich, Rämistrasse 100, 8091 Zurich (CH), Switzerland.

出版信息

Data Brief. 2025 Apr 10;60:111546. doi: 10.1016/j.dib.2025.111546. eCollection 2025 Jun.

Abstract

With this update, we add 164 patients with newly diagnosed oropharyngeal squamous cell carcinoma (OPSCC) from the University Hospital Vall d'Hebron (HVH) in Barcelona, Spain, to the previously published cohort of 287 OPSCC patients from the University Hospital Zurich (USZ). For each patient, we report the clinical involvement of lymph node levels (LNLs) I-V and VII on both sides of the neck. LNL involvement is assessed separately for the available diagnostic modalities comprising computed tomography (CT), magnetic resonance imaging (MRI), and/or FDG-positron emission tomography (PET/CT). For 10 surgically treated patients, we also report pathological LNL involvement after neck dissection. Additionally, we report clinicopathological factors such as sex, age, alcohol and nicotine abuse, HPV status, TNM stage, tumor subsite (ICD-10 code) and tumor volume, and whether the tumor extended over the mid-sagittal plane. The additional data is made available in the same CSV file format as the records of the initial dataset. The new data represents a valuable update to the original records that substantially increases the size of the cohort. In addition, it allows assessing differences between datasets, which provides information on potential patient biases. Due to the same data format, it is straightforward to reproduce any analysis that was done on the original data with the extended dataset.

摘要

通过此次更新,我们将来自西班牙巴塞罗那瓦尔德希伯伦大学医院(HVH)的164例新诊断的口咽鳞状细胞癌(OPSCC)患者加入到之前发表的来自苏黎世大学医院(USZ)的287例OPSCC患者队列中。对于每例患者,我们报告颈部两侧I-V和VII区淋巴结水平(LNLs)的临床受累情况。对于包括计算机断层扫描(CT)、磁共振成像(MRI)和/或氟代脱氧葡萄糖正电子发射断层扫描(PET/CT)在内的可用诊断方式,分别评估LNL受累情况。对于10例接受手术治疗的患者,我们还报告了颈清扫术后的病理LNL受累情况。此外,我们报告临床病理因素,如性别、年龄、酒精和尼古丁滥用情况、HPV状态、TNM分期、肿瘤亚部位(ICD-10编码)和肿瘤体积,以及肿瘤是否越过正中矢状面。额外数据以与初始数据集记录相同的CSV文件格式提供。新数据是对原始记录的一次有价值的更新,大幅增加了队列规模。此外,它允许评估数据集之间的差异,这提供了有关潜在患者偏差的信息。由于数据格式相同,使用扩展数据集重现对原始数据进行的任何分析都很简单。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab95/12175227/7a680e718de2/gr1.jpg

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