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高血压患者饮食营养摄入与睡眠障碍之间的关联:2005 - 2020年美国国家健康与营养检查调查(NHANES)的横断面研究

Association between dietary nutrient intake and sleep disorders in hypertensive patients: a cross-sectional study of NHANES, 2005-2020.

作者信息

Tian Aokai, Zheng Yafang, Jin Jing, Huang Chunyuan

机构信息

Liaoning University of Traditional Chinese Medicine, Shenyang, Liaoning, China.

出版信息

Front Nutr. 2025 Jun 4;12:1586530. doi: 10.3389/fnut.2025.1586530. eCollection 2025.

DOI:10.3389/fnut.2025.1586530
PMID:40535038
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12173896/
Abstract

BACKGROUND

Dietary nutrient intake is critical for healthy sleep patterns, but studies in hypertensive patients are lacking. This study examines the connection between hypertension patients' and their dietary nutrient intake.

METHODS

Adults with complete data on hypertension, dietary nutrient intake, and sleep disorders from the 2005 to 2020 National Health and Nutrition Examination Survey (NHANES) were used. The association between dietary nutrient intake and sleep disorders in hypertensive patients was assessed by multivariable logistic regression, smoothed curve fitting, subgroup analyses, interaction tests, and threshold effect analyses.

RESULTS

There were altogether 15,871 subjects included in this work, with 5,791 individuals presenting with sleep disorders. The positive associations of dietary sugar, fat, and calcium intake with sleep disorders remained stable in fully adjusted models. Analyses of subgroups indicated that the link between sugar consumption and sleep disorders was affected by both gender and diabetes, while the connection between fat consumption and sleep disorders was influenced by gender alone. In female patients, a U-shaped association was observed between dietary sugar, fat intake, and sleep disorders, with inflection points of 140 and 66, respectively. Finally, the relationships between dietary sugar, fat, and calcium intake and various types of sleep disorders were further analyzed. The findings indicated that the intake of dietary sugar was correlated with other types of sleep, and dietary calcium intake was correlated with restless legs syndrome.

CONCLUSION

Our results indicate that the increased risk of sleep disorders in hypertensive patients may be associated with increased dietary sugar, fat, and calcium intake.

摘要

背景

饮食营养摄入对健康的睡眠模式至关重要,但高血压患者的相关研究尚缺。本研究探讨高血压患者与其饮食营养摄入之间的联系。

方法

采用2005年至2020年美国国家健康与营养检查调查(NHANES)中具有高血压、饮食营养摄入和睡眠障碍完整数据的成年人。通过多变量逻辑回归、平滑曲线拟合、亚组分析、交互作用检验和阈值效应分析评估高血压患者饮食营养摄入与睡眠障碍之间的关联。

结果

本研究共纳入15871名受试者,其中5791人存在睡眠障碍。在完全调整模型中,饮食中糖、脂肪和钙的摄入量与睡眠障碍的正相关关系保持稳定。亚组分析表明,糖摄入与睡眠障碍之间的联系受性别和糖尿病两者影响,而脂肪摄入与睡眠障碍之间的联系仅受性别影响。在女性患者中,饮食中糖、脂肪摄入量与睡眠障碍之间呈U形关联,拐点分别为140和66。最后,进一步分析了饮食中糖、脂肪和钙的摄入量与各类睡眠障碍之间的关系。结果表明,饮食中糖的摄入与其他类型的睡眠有关,饮食中钙的摄入与不安腿综合征有关。

结论

我们的结果表明,高血压患者睡眠障碍风险增加可能与饮食中糖、脂肪和钙的摄入量增加有关。

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