Mohammadian Manijeh, Jalouti Nima, Yazdanian Mohsen, Keykha Elham, Hajisadeghi Samira
Department of Dental Biomaterials, School of Dentistry, Alborz University of Medical Sciences, Karaj, Iran.
Department of Dental Biomaterials, School of Dentistry, Iran University of Medical Sciences, Tehran, Iran.
Front Oral Health. 2025 Jun 5;6:1550127. doi: 10.3389/froh.2025.1550127. eCollection 2025.
Dentin hypersensitivity (DH) has long been a challenging condition, with many treatment methods showing limited success. However, the emergence of laser therapy, particularly the significant potential of diode laser (DL) and sodium fluoride (NaF) varnish, has sparked new hope. This research is a significant step towards a more effective treatment for DH, aiming to evaluate the promising potential of DL in treating DH, both independently and in combination with fluoride varnish. By delving into this research, you are investing your time in understanding a crucial advancement in the field of dentistry.
A comprehensive search was conducted across the PubMed, Scopus, and Web of Science databases, including studies published up until May 2024. Randomized clinical trials that assessed DH using a visual analog scale (VAS) score were included. Data on participant demographics, treatment types, and VAS scores were extracted by two reviewers. The risk of bias was assessed using the revised Cochrane risk-of-bias instrument for randomized trials (RoB-2).
Three studies met the inclusion criteria, comparing NaF varnish, DL, and their combination. Both DL and the combination of DL and NaF varnish were more effective than NaF varnish alone in reducing DH. The combined treatment showed marginally superior outcomes compared to DL alone. Significant reductions in DH were observed across all treatment groups, with the combination therapy demonstrating the most substantial and consistent improvement.
Diode laser therapy, particularly when combined with NaF varnish, represents a promising treatment approach for DH, offering superior efficacy over NaF varnish alone. These findings suggest that combination therapy may provide longer-lasting relief, with implications for improving clinical outcomes in DH management.
牙本质过敏症（DH）长期以来一直是一种具有挑战性的病症，许多治疗方法的成功率有限。然而，激光治疗的出现，尤其是二极管激光（DL）和氟化钠（NaF） varnish的巨大潜力，带来了新的希望。这项研究是朝着更有效治疗DH迈出的重要一步，旨在评估DL单独以及与氟化物varnish联合治疗DH的潜在前景。通过深入研究这项研究，您正在投入时间了解牙科领域的一项关键进展。
在PubMed、Scopus和Web of Science数据库中进行了全面搜索，包括截至2024年5月发表的研究。纳入使用视觉模拟量表（VAS）评分评估DH的随机临床试验。由两名评审员提取有关参与者人口统计学、治疗类型和VAS评分的数据。使用修订后的Cochrane随机试验偏倚风险工具（RoB - 2）评估偏倚风险。
三项研究符合纳入标准，比较了NaF varnish、DL及其组合。DL以及DL与NaF varnish的组合在减轻DH方面均比单独使用NaF varnish更有效。联合治疗与单独使用DL相比显示出略优的结果。在所有治疗组中均观察到DH显著降低，联合治疗显示出最显著和一致的改善。
二极管激光治疗，特别是与NaF varnish联合使用时，是一种有前景的DH治疗方法，比单独使用NaF varnish具有更高的疗效。这些发现表明联合治疗可能提供更持久的缓解，对改善DH管理的临床结果具有重要意义。
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