Chen Jing, Hu Qing, Hu Jiajie, Liu Songtao, Yin Linyu
Department of Rehabilitation Medicine, Affiliated Hospital (Clinical College) of Xiangnan University, Xiangnan University, Chenzhou, Hunan, People's Republic of China.
College of Medical Imaging Laboratory and Rehabilitation, Xiangnan University, Chenzhou, Hunan, People's Republic of China.
J Pain Res. 2025 Jun 15;18:2993-3008. doi: 10.2147/JPR.S519242. eCollection 2025.
Delayed-onset muscle soreness (DOMS) is a common clinical condition that frequently affects various populations. Physical therapy offers distinct advantages in managing this condition. However, many recently published studies have produced conflicting results and lack compelling evidence, complicating clinicians' decision making. We employed a Bayesian meta-analysis to assess the efficacy and safety of physical therapy modalities (PTMs) for DOMS, aiming to provide robust, evidence-based medical insights for clinical application.
We conducted a comprehensive search for randomized controlled trials (RCTs) evaluating PTMs for DOMS across databases, including CNKI, CSCD, CCD, CBM, PubMed, EMbase, Cochrane Library, and Web of Science, until October 22, 2024. The included studies were assessed for risk of bias using the Cochrane Risk of Bias Assessment tool, tailored for RCTs. A network meta-analysis was performed using R v.4.2.2.
At 24 hours post-intervention, photobiomodulation therapy(PBMT) demonstrated a significant advantage over placebo (-3.91 [-5.57, -2.17],P<0.05). The effects of other therapies were not significant (Cryotherapy: -0.58 (-1.20, 0.11), Cryotherapy combined with PBMT: 0.48 (-1.09, 2.01), ES: -0.98 (-2.82, 0.89), Irradiated: -0.10 (-1.71, 1.53), STM: -0.89 (-2.63, 0.85), UT: -0.61 (-1.92, 0.84)).At 48 hours post-intervention, both PBMT (-5.24 [-6.95, -3.20],P<0.05) and sauna (-3.29 [-6.21,-0.33],P<0.05) exhibited significant effects compared to placebo.The effects of other therapies were not statistically significant.; However, beyond 48 hours, there was no notable benefit from PTMs when compared with placebo, indicating that PTMs are more effective within the initial 48 hours, with PBMT yielding superior outcomes.
The findings from this investigation indicate that PBMT and sauna treatment produce significant effects within the first 48 hours; however, beyond this period, the impact of photobiomodulation diminishes significantly. Overall, physical therapy modalities are the most effective within the 48-h window.
延迟性肌肉酸痛（DOMS）是一种常见的临床病症，常影响不同人群。物理治疗在管理这种病症方面具有显著优势。然而，许多最近发表的研究结果相互矛盾且缺乏令人信服的证据，这使得临床医生的决策变得复杂。我们采用贝叶斯荟萃分析来评估物理治疗方式（PTMs）对DOMS的疗效和安全性，旨在为临床应用提供有力的、基于证据的医学见解。
我们对评估PTMs治疗DOMS的随机对照试验（RCTs）进行了全面检索，检索数据库包括中国知网（CNKI）、中国科学引文数据库（CSCD）、中国生物医学文献数据库（CBM）、中国生物医学期刊数据库（CCD）、PubMed、EMbase、Cochrane图书馆和Web of Science，检索截至2024年10月22日。使用针对RCTs量身定制的Cochrane偏倚风险评估工具对纳入研究的偏倚风险进行评估。使用R v.4.2.2进行网络荟萃分析。
干预后24小时，光生物调节疗法（PBMT）与安慰剂相比显示出显著优势（-3.91 [-5.57, -2.17]，P<0.05）。其他疗法的效果不显著（冷冻疗法：-0.58 [-1.20, 0.11]；冷冻疗法联合PBMT：0.48 [-1.09, 2.01]；电刺激：-0.98 [-2.82, 0.89]；照射：-0.10 [-1.71, 1.53]；软组织手法：-0.89 [-2.63, 0.85]；超声疗法：-0.61 [-1.92, 0.84]）。干预后48小时，PBMT（-
