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急性冠状动脉综合征入住急性心脏监护病房女性患者临床及流行病学特征分析:并发症预测因素

Analysis of Clinical and Epidemiological Profiles as Predictors of Complications in Women Admitted to the Acute Cardiac Care Unit for Acute Coronary Syndrome.

作者信息

Parellada-Vendrell Marta, Pérez-Ortega Sílvia, Romeu-Mirabete Nuria, Prat-Masana Montserrat, Venturas Montserrat, Zabalegui Adelaida, Andrea Rut

机构信息

Acute Cardiac Care Unit, Cardiovascular Clinical Institute, Hospital Clínic of Barcelona, Barcelona, Spain.

University of Barcelona, Barcelona, Spain.

出版信息

Womens Health Rep (New Rochelle). 2025 May 8;6(1):527-538. doi: 10.1089/whr.2025.0005. eCollection 2025.

Abstract

INTRODUCTION

In women, cardiovascular disease accounts for 35% of annual deaths, with ischemic heart disease being the leading cause. There are knowledge gaps in research, prevention, treatment, and access to cardiovascular care in women.

OBJECTIVES

To describe the clinical and epidemiological profiles of women with acute coronary syndrome (ACS) admitted to an Acute Cardiac Care Unit (ACCU) and to study their association with the development of complications.

METHODS

This descriptive study included women admitted to the ACCU of a tertiary hospital for ACS. Sociodemographic, anthropometric, and clinical variables were assessed. Descriptive and inferential statistical analyses were performed using the SPSS v25 software.

RESULTS

Eighty women (mean age, 68 ± 13 years) with a high prevalence of cardiovascular risk factors were included, and 66.2% presented ST-segment elevation ACS. The prevailing symptom was chest pain in 96.3% of patients, followed by associated symptoms such as sweating, nausea, and dyspnea (86.3%). The etiology was secondary to obstructive coronary artery disease in 81.3%, and the therapeutic strategy was percutaneous coronary intervention in 72.5% of patients. Among the women, 64.1% attributed their symptoms to non-cardiac causes, 60% did not perceive severity, and 35.2% presented complications of ACS, particularly cardiac arrest and arrhythmias. A reduced ejection fraction and being alone at the onset of symptoms were associated with a higher risk of complications.

CONCLUSIONS

Despite severe clinical presentations and complications, women have a low perception of severity and attribute cardiovascular symptoms to non-cardiac causes. Increasing awareness of ACS and its complications in women is needed among the population in order to improve health outcomes.

摘要

引言

在女性中,心血管疾病占年度死亡人数的35%,缺血性心脏病是主要原因。在女性心血管疾病的研究、预防、治疗以及获得心血管护理方面存在知识空白。

目的

描述入住急性心脏护理单元(ACCU)的急性冠状动脉综合征(ACS)女性患者的临床和流行病学特征,并研究其与并发症发生的关联。

方法

这项描述性研究纳入了因ACS入住三级医院ACCU的女性患者。评估了社会人口统计学、人体测量学和临床变量。使用SPSS v25软件进行描述性和推断性统计分析。

结果

纳入了80名心血管危险因素患病率较高的女性(平均年龄68±13岁),66.2%表现为ST段抬高型ACS。96.3%的患者主要症状为胸痛,其次是出汗、恶心和呼吸困难等相关症状(86.3%)。81.3%的病因继发于阻塞性冠状动脉疾病,72.5%的患者治疗策略为经皮冠状动脉介入治疗。在这些女性中,64.1%将其症状归因于非心脏原因,60%未意识到病情严重程度,35.2%出现了ACS并发症,尤其是心脏骤停和心律失常。射血分数降低以及症状发作时独自一人与并发症风险较高相关。

结论

尽管临床表现严重且有并发症,但女性对病情严重程度的认知较低,并将心血管症状归因于非心脏原因。为改善健康结局,需要提高人群对女性ACS及其并发症的认识。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f1dc/12177328/e2eff7bfe42d/whr.2025.0005_figure1.jpg

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