Jiang Shu-Min, Huang Lu, Jiang Quan
Department of Hepatobiliary Surgery, The First Affiliated Hospital of Jinan University, Guangzhou, China.
Front Oncol. 2025 Jun 5;15:1548570. doi: 10.3389/fonc.2025.1548570. eCollection 2025.
Intrahepatic cholangiocarcinoma (ICC) is a primary liver cancer with insidious onset, rapid progression, and poor prognosis. The lymphatic system is the main route of ICC distant metastasis, with lungs, adrenal glands, and brain as the most common extrahepatic sites. However, extrahepatic metastases of ICC have rarely been reported in patients with rectal symptoms as initial symptoms, and the diagnosis relies on the specific immunohistochemical features of intestinal lesion biopsy. Herein, this study presents an incidental case of ICC with rectal metastasis to investigate its characteristics based on its diagnosis, metastasis, and treatment.
肝内胆管癌(ICC)是一种起病隐匿、进展迅速且预后较差的原发性肝癌。淋巴系统是ICC远处转移的主要途径,肺、肾上腺和脑是最常见的肝外转移部位。然而,以直肠症状为首发症状的ICC肝外转移鲜有报道,其诊断依赖于肠道病变活检的特定免疫组化特征。在此,本研究报告一例ICC伴直肠转移的偶发病例,以基于其诊断、转移和治疗情况探讨其特征。