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成人隐匿性自身免疫性糖尿病:老年患者的诊断挑战

Latent Autoimmune Diabetes in Adults: A Diagnostic Challenge in Elderly Patients.

作者信息

Monteiro Filipa, Artilheiro Catarina, Shara Tetiana, Andrade Maria Teresa, Santos Leticia, Nunes Andreia, Ramalho Sara, Escarigo Conceição

机构信息

Internal Medicine, Garcia de Orta Hospital, Almada, PRT.

出版信息

Cureus. 2025 May 20;17(5):e84457. doi: 10.7759/cureus.84457. eCollection 2025 May.

Abstract

Diabetes mellitus (DM) is a chronic condition with several subtypes that differ in etiology and clinical progression. Type 2 diabetes (T2DM) is the most commonly diagnosed form and is closely linked to obesity and physical inactivity, while type 1 diabetes (T1DM) is largely autoimmune in origin. A less understood subtype, latent autoimmune diabetes in adults (LADA), shares characteristics of both T2DM and T1DM and is often misdiagnosed as T2DM. This article presents three clinical cases of elderly patients misdiagnosed with T2DM, but who actually had LADA, highlighting the challenges associated with its early identification and the importance of more accurate diagnostic approaches.

摘要

糖尿病(DM)是一种慢性疾病,有几种亚型,其病因和临床进展各不相同。2型糖尿病(T2DM)是最常见的诊断形式,与肥胖和缺乏身体活动密切相关,而1型糖尿病(T1DM)在很大程度上起源于自身免疫。一种了解较少的亚型,成人隐匿性自身免疫性糖尿病(LADA),兼具T2DM和T1DM的特征,常被误诊为T2DM。本文介绍了三例老年患者被误诊为T2DM但实际患有LADA的临床病例,突出了早期识别LADA的挑战以及更准确诊断方法的重要性。

相似文献

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Interventions for latent autoimmune diabetes (LADA) in adults.成人潜伏性自身免疫性糖尿病(LADA)的干预措施。
Cochrane Database Syst Rev. 2007 Jul 18(3):CD006165. doi: 10.1002/14651858.CD006165.pub2.

本文引用的文献

1
Latent Autoimmune Diabetes in Adults: A Case Report.成人隐匿性自身免疫性糖尿病:一例报告
Oman Med J. 2024 Jan 31;39(1):e596. doi: 10.5001/omj.2024.05. eCollection 2024 Jan.
2
A Review on Latent Autoimmune Diabetes in Adults.成人隐匿性自身免疫性糖尿病综述
Cureus. 2023 Oct 29;15(10):e47915. doi: 10.7759/cureus.47915. eCollection 2023 Oct.

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