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麻醉诱导后隐匿性支气管胸膜瘘患者紧急使用舒更葡糖钠的情况

Urgent Use of Sugammadex in a Patient With Occult Bronchopleural Fistula Manifested Following Anesthesia Induction.

作者信息

Suzuki Takashi, Ishii Mizue, Sakazaki Reina, Nagane Daiki, Ogaku Akiko

机构信息

Department of Anesthesiology, Showa Medical University Koto Toyosu Hospital, Tokyo, JPN.

Department of Anesthesia and Intensive Care Medicine, National Cancer Center Hospital, Tokyo, JPN.

出版信息

Cureus. 2025 May 19;17(5):e84431. doi: 10.7759/cureus.84431. eCollection 2025 May.

Abstract

Sugammadex could play a significant role in managing the "cannot intubate, cannot ventilate" scenarios. However, the urgent use of sugammadex in intubated patients after induction of anesthesia is uncommon. We report the case of an 85-year-old, 45 kg man with a history of pulmonary resection for lung cancer and open window thoracostomy for postoperative pyothorax. He underwent a ureteral stent exchange for ureteral calculi. During anesthesia induction, 40 mg of rocuronium was administered, followed by uneventful mask ventilation and tracheal intubation. Subsequent mechanical ventilation failed due to massive air leakage from an occult bronchopleural fistula in the left chest wall that manifested following anesthesia induction. However, oxygenation was maintained with oxygen-air insufflation from the anesthesia machine by closing the adjustable pressure-limiting valve and maximizing fresh gas flow. Although the tracheal tube was blindly advanced with the intention of one-lung ventilation via the right lung, it was unsuccessful. Subsequently, 200 mg of sugammadex was administered to reverse the rocuronium effect, allowing the continuation of anesthesia with desflurane under spontaneous breathing. High-flow oxygen-air insufflation via a tracheal tube and urgent, but not critical, use of sugammadex to restore spontaneous breathing were helpful for the anesthetic management of this patient who developed a massive air leak due to an occult bronchopleural fistula that manifested following anesthesia induction.

摘要

舒更葡糖钠在处理“无法插管、无法通气”的情况中可能发挥重要作用。然而,在麻醉诱导后对已插管患者紧急使用舒更葡糖钠的情况并不常见。我们报告一例85岁、体重45千克的男性患者,有因肺癌行肺切除术及因术后脓胸行开窗胸廓造口术的病史。他因输尿管结石接受输尿管支架置换术。麻醉诱导期间,给予40毫克罗库溴铵,随后面罩通气和气管插管顺利。麻醉诱导后,由于左胸壁隐匿性支气管胸膜瘘大量漏气,随后的机械通气失败。然而,通过关闭可调压力限制阀并最大化新鲜气体流量,利用麻醉机进行氧空气吹入维持了氧合。尽管试图通过右肺进行单肺通气而盲目推进气管导管,但未成功。随后,给予200毫克舒更葡糖钠以逆转罗库溴铵的作用,从而在自主呼吸下继续使用地氟醚麻醉。通过气管导管进行高流量氧空气吹入以及紧急但非关键地使用舒更葡糖钠恢复自主呼吸,有助于对该因麻醉诱导后出现隐匿性支气管胸膜瘘而发生大量漏气的患者进行麻醉管理。

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