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胰岛素依赖型糖尿病发病时的医疗模式:与严重程度及后续并发症的关联

Medical care patterns at the onset of insulin-dependent diabetes mellitus: association with severity and subsequent complications.

作者信息

Hamman R F, Cook M, Keefer S, Young W F, Finch J L, Lezotte D, McLaren B, Orleans M, Klingensmith G, Chase H P

出版信息

Diabetes Care. 1985 Sep-Oct;8 Suppl 1:94-100. doi: 10.2337/diacare.8.1.s94.

Abstract

The hospitalization of a child at the onset of insulin-dependent diabetes mellitus (IDDM) has become routine in many parts of the world, although controversy exists about its necessity. We examined the patterns of medical care use and the prognosis for acute complications after diagnosis for children with newly diagnosed IDDM in Colorado from 1978 to 1982. We reasoned that if children cared for entirely in outpatient settings at diagnosis had no more frequent acute complications after diagnosis than hospitalized children, we would be encouraged to further explore other potential benefits of outpatient care at onset. Twelve percent of 305 children studied statewide received only outpatient care during the first 2 wk after diagnosis, and, prognostically, their subsequent hospitalization and ketoacidosis rates were 2-3.7 times lower than those of children who received any inpatient care. No differences were noted for severe insulin reaction rates. Children classified as "severe" at onset, or with parents of lower education and income, or aged 10-14 yr at onset, regardless of care setting, had 2-4 times higher subsequent acute complication rates after onset than children without these characteristics. These findings, together with data on nights hospitalized and average length of stay in hospital at onset, suggest that a 42% reduction in total nights hospitalized could occur if children with "mild" or "normal" severity at onset were treated largely in the outpatient setting.

摘要

在世界许多地方,胰岛素依赖型糖尿病(IDDM)发病时儿童住院已成为常规做法,尽管对于其必要性存在争议。我们研究了1978年至1982年科罗拉多州新诊断为IDDM的儿童在诊断后的医疗护理使用模式及急性并发症的预后情况。我们推断,如果诊断时完全在门诊接受护理的儿童在诊断后发生急性并发症的频率不高于住院儿童,我们将受到鼓舞去进一步探索发病时门诊护理的其他潜在益处。在全州范围内研究的305名儿童中,12%在诊断后的头2周仅接受门诊护理,从预后情况来看,他们随后的住院率和酮症酸中毒率比接受过任何住院护理的儿童低2至3.7倍。严重胰岛素反应率未发现差异。发病时被归类为“严重”的儿童,或父母教育程度和收入较低的儿童,或发病时年龄在10至14岁的儿童,无论护理环境如何,发病后随后的急性并发症发生率比没有这些特征的儿童高2至4倍。这些发现,连同发病时住院的夜晚数和平均住院天数的数据表明,如果发病时“轻度”或“正常”严重程度的儿童主要在门诊接受治疗,住院总夜晚数可能会减少42%。

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