Wharrad H J, Birmingham A T, Macdonald I A, Inch P J, Mead J L
Eur J Clin Pharmacol. 1985;29(1):37-43. doi: 10.1007/BF00547366.
The effect of finger tremor of the administration of 150 mg of caffeine three times daily for two days was measured using an accelerometer in 7 healthy subjects taking their normal diet (excluding caffeine-containing beverages). The effect on finger tremor of a short period of fasting with and without the 450 mg daily dose of caffeine was also studied in the same 7 subjects. Fasting increased finger tremor significantly when caffeine was administered. In doses comparable to the likely adult daily intake in this country, caffeine did not increase finger tremor whilst subjects were taking their normal diet.
在7名正常饮食(不包括含咖啡因饮料)的健康受试者中,使用加速度计测量了连续两天每日三次服用150毫克咖啡因对手指震颤的影响。还在这7名受试者中研究了短期禁食且有或无每日450毫克咖啡因剂量时对手指震颤的影响。当给予咖啡因时,禁食会显著增加手指震颤。在与该国成年人可能的每日摄入量相当的剂量下,当受试者正常饮食时,咖啡因不会增加手指震颤。