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红色发射碳点作为用于高氯酸特异性传感与成像的荧光探针。

Red Emissive Carbon Dots as Fluorescent Probe for Specific Sensing and Imaging of HCIO.

作者信息

Peng Ying, Yang Haonan, Qu Mengyao, Zhang Shaobing, Yang Zheng, Jia Xiaodan, Wang Bo, Liu Xiangrong

机构信息

College of Chemistry and Chemical Engineering, Xi'an University of Science and Technology, Xi'an, 710054, P. R. China.

Key Laboratory of Coal Resources Exploration and Comprehensive Utilization, Ministry of Land and Resources, Xi'an, 710012, P. R. China.

出版信息

J Fluoresc. 2025 Jun 21. doi: 10.1007/s10895-025-04411-x.

Abstract

Selective detecting and tracking of HClO is crucial for reflecting related oxidative stress process and environmental safety. In this research, we present the red emissive carbon dots (CDs) with advantageous optical performances including high fluorescent stability, strong intensity and advanced quantum yield. The CDs showed excellent selectivity and sensitivity towards HClO with superior anti-interference performance and outstanding detection limit, indicating the CDs based fluorescent nanoprobe is not only highly suitable for detecting HClO in complicated water samples by solution, but also serve as prospective fluorescent filer paper sensor for fast detection. The low cytotoxicity and favorable biocompatibility are extremely demanded for sensing and imaging exogenous and endogenous HClO in living cells, and encourages the CDs as powerful imaging tool to unveil the mystery of HClO participant oxidative stress process, which would be beneficial for early diagnosis and therapeutics of related diseases. Clinical Trial Number Not applicable.

摘要

选择性检测和跟踪次氯酸对于反映相关氧化应激过程和环境安全至关重要。在本研究中,我们展示了具有优异光学性能的红色发光碳点(CDs),包括高荧光稳定性、强强度和先进的量子产率。这些碳点对次氯酸表现出优异的选择性和灵敏度,具有卓越的抗干扰性能和出色的检测限,表明基于碳点的荧光纳米探针不仅非常适合通过溶液检测复杂水样中的次氯酸,而且还可作为用于快速检测的前瞻性荧光滤纸传感器。在活细胞中传感和成像外源性和内源性次氯酸时,极低的细胞毒性和良好的生物相容性是极其必要的,这促使碳点成为揭示次氯酸参与氧化应激过程奥秘的强大成像工具,这将有利于相关疾病的早期诊断和治疗。临床试验编号:不适用。

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