Kulikauskas V, Blaustein D, Ablin R J
Fertil Steril. 1985 Oct;44(4):526-8. doi: 10.1016/s0015-0282(16)48925-9.
The possible effects of cigarette smoking on sperm were evaluated by comparison of the quality of sperm from 103 smokers and 135 nonsmokers in a blind study. Smokers were found to possess significantly (P less than 0.001) decreased density (number) and motility of their sperm than nonsmokers. Morphologic abnormalities, particularly bicephalia, although prevalent among individual smokers, did not differ significantly (P greater than 0.9) when a comparison of smokers versus nonsmokers was made as a whole. Based on these observations and those of others demonstrating the presence of the mutagenic properties of smoke condensates, we suggest that decreases in sperm density and motility in cigarette smokers may be reflective of smoke condensate-induced mutagenic spermatogenital alterations.
在一项盲法研究中，通过比较103名吸烟者和135名非吸烟者的精子质量，评估了吸烟对精子可能产生的影响。结果发现，吸烟者精子的密度（数量）和活力明显低于非吸烟者（P<0.001）。形态学异常，特别是双头畸形，虽然在个体吸烟者中普遍存在，但总体比较吸烟者和非吸烟者时，差异不显著（P>0.9）。基于这些观察结果以及其他表明烟雾冷凝物具有致突变特性的研究，我们认为吸烟者精子密度和活力的降低可能反映了烟雾冷凝物诱导的致突变性生精改变。
