Tosyali Merve, Koc Feyza, Dortkardesler Burce Emine, Gokce Sule
Department of Pediatrics, Division of Social Pediatrics, Faculty of Medicine, Ege University, Bornova, Izmir, Turkey.
Department of Pediatrics, Division of General Pediatrics, Faculty of Medicine, Ege University, Izmir, Turkey.
J Health Popul Nutr. 2025 Jun 21;44(1):217. doi: 10.1186/s41043-025-00979-z.
Vitamin A deficiency is an important public health problem worldwide, especially in undeveloped and developing countries. Vitamin A deficiency; It can cause visual disorders, growth retardation, as well as cellular and humoral immunological disorders. We aimed to evaluate vitamin A levels in hospitalized patients and to determine the factors that may be related to vitamin A deficiency.
Children between the ages of 2 months and 18 years admitted to Ege University Faculty of Medicine, General Pediatrics Unit in 2017-2020 were included. Three hundred sixty patients with vitamin A levels were evaluated retrospectively.
The mean serum vitamin A level of the study group was 413.6 ± 187.7. Serum vitamin A level was found to be below 316 µg/L (low) in 89 (24.7%), and within normal limits in 271 (75.3%) of the 360 patients. In 62 (69.6%) of the patients with low vitamin A levels, vitamin A was found to be in the marginal range, while in 27 (30.4%) patients, it was below 200 µg/L. Malnutrition was found in 98 (27.2%) of 360 patients included in the study.
Vitamin A deficiency may be observed in hospitalized children. Detailed evaluation of each patient, especially in developing countries, will prevent vitamin A deficiencies and malnutrition.
维生素A缺乏是全球一个重要的公共卫生问题，尤其是在不发达国家和发展中国家。维生素A缺乏会导致视力障碍、生长发育迟缓以及细胞和体液免疫紊乱。我们旨在评估住院患者的维生素A水平，并确定可能与维生素A缺乏相关的因素。
纳入2017年至2020年在伊兹密尔大学医学院普通儿科病房住院的2个月至18岁儿童。对360例有维生素A水平数据的患者进行回顾性评估。
研究组血清维生素A平均水平为413.6±187.7。在360例患者中，89例（24.7%）血清维生素A水平低于316μg/L（低水平），271例（75.3%）在正常范围内。在维生素A水平低的患者中，62例（69.6%）维生素A处于边缘范围，27例（30.4%）低于200μg/L。在纳入研究的360例患者中，98例（27.2%）存在营养不良。
住院儿童中可能存在维生素A缺乏。对每位患者进行详细评估，尤其是在发展中国家，将预防维生素A缺乏和营养不良。
