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小鼠下颌骨尺寸缩放模式的遗传分析。

Genetic analysis of size-scaling patterns in the mouse mandible.

作者信息

Atchley W R, Plummer A A, Riska B

出版信息

Genetics. 1985 Nov;111(3):579-95. doi: 10.1093/genetics/111.3.579.

Abstract

The relationship between multidimensional form of the adult mouse mandible and body size is examined from an ontogenetic perspective. The origin and ontogeny of phenotypic correlations are described in terms of genetic and environmental covariance patterns between adult skeletal morphology and growth in body weight. Different ontogenetic patterns are observed in the genetic correlations, and these can be related to the developmental as well as the functional aspects of mandibular form. The quantitative genetic aspects of craniomandibular growth and morphogenesis are explored, together with an examination of the impact of ontogenetic changes in the genetic variance-covariance structure on morphogenetic integration and evolution by selection.

摘要

从个体发育的角度研究成年小鼠下颌骨的多维形态与体型之间的关系。根据成年骨骼形态与体重增长之间的遗传和环境协方差模式,描述了表型相关性的起源和个体发育。在遗传相关性中观察到不同的个体发育模式,这些模式可能与下颌骨形态的发育和功能方面有关。探讨了颅下颌生长和形态发生的数量遗传学方面,同时研究了遗传方差-协方差结构的个体发育变化对形态发生整合和选择进化的影响。

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