利妥昔单抗治疗HIV阳性患者系统性硬化症的疗效：一则新病例报告

Gupta Sunil Kumar, Rana Shiwangi, Bajoria Sapna

Department of Dermatology and Venereology, All India Institute of Medical Sciences, Gorakhpur, Uttar Pradesh, India.

Indian J Sex Transm Dis AIDS. 2025 Jan-Jun;46(1):80-83. doi: 10.4103/ijstd.ijstd_36_25. Epub 2025 Jun 9.

HIV infection presents a variety of symptoms, including connective tissue disorders. Systemic sclerosis (SSc) with HIV is rarely reported, with limited literature. We present a 45-year-old female with HIV on HAART who developed diffuse cutaneous SSc. She was successfully treated with rituximab, showing significant improvement in cutaneous manifestations.

HIV感染会出现多种症状，包括结缔组织疾病。合并HIV的系统性硬化症（SSc）鲜有报道，相关文献有限。我们报告了一名45岁接受高效抗逆转录病毒治疗（HAART）的HIV感染女性，她患上了弥漫性皮肤型SSc。她接受利妥昔单抗治疗后获得成功，皮肤表现有显著改善。