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患人类疱疹病毒6型的儿童与贝尔麻痹:病例报告及文献综述

Child With Human Herpesvirus 6 and Bell's Palsy: Case Report and Overview of the Literature.

作者信息

Adler Loren, Schroeder Avery, Carney Paul

机构信息

Medical School, University of Missouri School of Medicine, Columbia, USA.

Pediatrics and Neurology, University of Missouri School of Medicine, Columbia, USA.

出版信息

Cureus. 2025 May 21;17(5):e84563. doi: 10.7759/cureus.84563. eCollection 2025 May.

Abstract

Peripheral facial nerve palsy (pFP), or Bell's palsy, does occur in the pediatric population, although it is rare. Numerous infectious etiologies of pFP are known, but up to 75% of pediatric pFP cases are idiopathic. Empiric treatment typically involves steroids and antivirals, and etiologic testing is not frequently conducted. Human herpesvirus 6 (HHV-6) has been reported as a possible cause of pFP in both adults and children. We report a case of a 17-month-old female who presented with pFP and had a history of HHV-6 infection five months prior to presentation. This case may represent another instance of HHV-6 as a potential causative agent of pFP. While it cannot be stated with certainty, this finding lends itself to the consideration of HHV-6 as a cause of pFP, both in the setting of acute infection and viral reactivation.

摘要

周围性面神经麻痹(pFP),即贝尔麻痹,确实会在儿童群体中出现,尽管较为罕见。已知pFP有多种感染性病因,但高达75%的儿童pFP病例为特发性。经验性治疗通常包括使用类固醇和抗病毒药物,且病因检测并不常见。人类疱疹病毒6型(HHV - 6)已被报道为成人和儿童pFP的可能病因。我们报告一例17个月大的女性病例,该患者出现pFP,且在发病前五个月有HHV - 6感染史。该病例可能代表HHV - 6作为pFP潜在病原体的又一实例。虽然不能确定,但这一发现有助于将HHV - 6视为急性感染和病毒再激活情况下pFP的病因进行考虑。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0d9e/12180606/f14af52d9086/cureus-0017-00000084563-i01.jpg

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