Russo Alida, Piletti Martina, Quinn Aidan J, Iacopino Daniela
Tyndall National Institute, University College Cork, Lee Maltings Complex, Dyke Parade, T12R5CP Cork, Ireland.
ACS Omega. 2025 Jun 6;10(23):24710-24719. doi: 10.1021/acsomega.5c01637. eCollection 2025 Jun 17.
Monitoring food quality requires the development of low-cost and sensitive analytical tools with label-free and point-of-site detection capabilities. Surface-enhanced Raman scattering (SERS) is a powerful analytical technique that combines fingerprint detection capabilities with high sensitivity. In this paper, we present the pen-on-paper fabrication of SERS substrates, whereby plasmonic nanoinks were written on a paper substrate and used for the detection of food contaminant residues. To construct sensitive and robust SERS sensors, four different nanoinks with different plasmonic properties were synthesized and tested on eight papers of different weights, textures, and hydrophilicities. The combination of silver nanoink and Bristol printing paper resulted in the strongest SERS substrate, which was used for crystal violet (CV) and tetracycline detection. Concentrations as low as 10 M were obtained for CV and 2.5 ppm of tetracycline in milk, showing the application potential of these paper-based SERS sensors for label-free detection of residuals in complex food matrices.
监测食品质量需要开发具有无标记和现场检测能力的低成本且灵敏的分析工具。表面增强拉曼散射（SERS）是一种强大的分析技术，它将指纹检测能力与高灵敏度相结合。在本文中，我们展示了基于纸的SERS基底的制造方法，即将等离子体纳米墨水书写在纸质基底上，并用于检测食品污染物残留。为构建灵敏且耐用的SERS传感器，合成了四种具有不同等离子体特性的纳米墨水，并在八张不同重量、质地和亲水性的纸张上进行了测试。银纳米墨水与布里斯托印刷纸的组合产生了最强的SERS基底，该基底用于结晶紫（CV）和四环素的检测。在牛奶中，CV的检测限低至10 M，四环素的检测限低至2.5 ppm，这表明这些基于纸的SERS传感器在复杂食品基质中无标记检测残留物方面具有应用潜力。
