Chachar Zaid, Xue Xiaoming, Fang Junteng, Chen Ming, Jiarui Chen, Chen Weiwei, Ahmed Nazir, Chachar Sadaruddin, Narejo Mehar-Un-Nisa, Ahmed Naseer, Fan Lina, Lai Ruiqiang, Qi Yongwen
College of Agriculture and Biology, Zhongkai University of Agriculture and Engineering, Guangzhou, China.
Institute of Nanfan and Seed Industry, Guangdong Academy of Science, Guangzhou, China.
Front Microbiol. 2025 Jun 6;16:1521422. doi: 10.3389/fmicb.2025.1521422. eCollection 2025.
, a Gram-negative bacterium, is the causative agent of bacterial wilt, a devastating disease affecting a wide range of economically important crops worldwide. This study explores the dynamic interactions between and its host plants, emphasizing key mechanisms underlying infection and host response. The pathogen initiates infection through root wounds or natural openings, rapidly colonizing xylem vessels where it forms biofilms that disrupt water and nutrient transport. Its virulence is driven by cell wall-degrading enzymes and effector proteins delivered via a Type III secretion system, which subvert plant immune responses and facilitate systemic spread. In turn, host plants activate hormonal and stress-related defense pathways, though these are often manipulated by the pathogen, leading to disease progression and reduced productivity. This review highlights critical gaps in our understanding of molecular host-pathogen interactions and the role of environmental conditions in disease development. Addressing these gaps is vital for improving management strategies, with breeding for resistance and advanced biotechnological tools offering promising solutions to combat bacterial wilt and support sustainable agriculture. Future research should focus on leveraging genetic insights to enhance host resistance, employing advanced biotechnological tools to develop crop varieties with enhanced resistance to , thereby promoting sustainable agriculture and strengthening global food security.
[未提及具体细菌名称]是一种革兰氏阴性菌，是细菌性枯萎病的病原体，细菌性枯萎病是一种毁灭性疾病，影响着全球范围内多种具有重要经济价值的作物。本研究探讨了[未提及具体细菌名称]与其寄主植物之间的动态相互作用，重点关注感染和寄主反应的关键机制。病原体通过根部伤口或自然开口引发感染，迅速定殖于木质部导管，在那里形成生物膜，扰乱水分和养分运输。其毒力由细胞壁降解酶和通过III型分泌系统传递的效应蛋白驱动，这些蛋白会破坏植物的免疫反应并促进系统性传播。反过来，寄主植物会激活激素和与胁迫相关的防御途径，尽管这些途径常常被病原体操纵，导致疾病进展和生产力下降。本综述强调了我们在理解分子寄主-病原体相互作用以及环境条件在疾病发展中的作用方面的关键差距。解决这些差距对于改进管理策略至关重要，培育抗性品种和先进的生物技术工具为对抗细菌性枯萎病和支持可持续农业提供了有前景的解决方案。未来的研究应专注于利用遗传学见解来增强寄主抗性，采用先进的生物技术工具培育对[未提及具体细菌名称]具有更强抗性的作物品种，从而促进可持续农业并加强全球粮食安全。
