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腹壁腺癌初次切除术后回顾性诊断为胆囊腺癌且原发灶不明:一例病例报告及文献复习

Gallbladder adenocarcinoma diagnosed retrospectively after initial resection of abdominal wall adenocarcinoma with unidentified primary source: a case report and review of the literature.

作者信息

Vignaroli Kendall, Perez Kevin, Guan Angel, Kim So Un, Raju Sharmila, Leach Carolyn, Ramiscal Judi Anne B

机构信息

Department of Surgical Oncology, Arrowhead Regional Medical Center, Colton, CA, United States.

Department of Laboratory Medicine, Arrowhead Regional Medical Center, Colton, CA, United States.

出版信息

Front Oncol. 2025 Jun 6;15:1609239. doi: 10.3389/fonc.2025.1609239. eCollection 2025.

DOI:10.3389/fonc.2025.1609239
PMID:40548113
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12179056/
Abstract

Gallbladder carcinoma is the most common malignancy found within the biliary tract and is most often diagnosed incidentally after cholecystectomy is performed. Port-site metastasis discovered after removal of gallbladder carcinoma is not entirely unusual; however, recommendations for the definitive management of these metastasis sites do not yet exist. We report a rare case of incisional site seeding diagnosed prior to the discovery of gallbladder adenocarcinoma in a healthy 59-year-old woman with a history of open cholecystectomy performed in a different country. Ultimately, this patient's case was staged as stage IVb disease as determined by an extensive multidisciplinary tumor board discussion and was managed with observation, frequent physical exams, and surveillance imaging. Our patient's survival is 2 years 7 months to date after index cholecystectomy. The management of our unprecedented case of gallbladder carcinoma diagnosed retrospectively after the initial discovery of incisional site metastasis is a difficult one, and the management of unique oncologic scenarios should utilize a multidisciplinary tumor board approach.

摘要

胆囊癌是胆道系统中最常见的恶性肿瘤,最常于胆囊切除术后偶然被诊断出来。胆囊癌切除术后发现的切口部位转移并不罕见;然而,对于这些转移部位的明确治疗方案尚无定论。我们报告了一例罕见病例,一名59岁健康女性,曾在国外接受过开腹胆囊切除术,在发现胆囊腺癌之前就诊断出了切口部位种植。最终,通过广泛的多学科肿瘤委员会讨论,该患者的病例被分期为IVb期,并采用观察、定期体格检查和监测成像进行管理。自首次胆囊切除术后,我们的患者至今已存活2年7个月。对于我们这例在最初发现切口部位转移后才回顾性诊断出胆囊癌的罕见病例,治疗颇具难度,对于独特的肿瘤情况,应采用多学科肿瘤委员会的方法进行管理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a90/12179056/b2a60115b551/fonc-15-1609239-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a90/12179056/8c26617ea123/fonc-15-1609239-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a90/12179056/3c4de1ee23f3/fonc-15-1609239-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a90/12179056/b2a60115b551/fonc-15-1609239-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a90/12179056/8c26617ea123/fonc-15-1609239-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a90/12179056/3c4de1ee23f3/fonc-15-1609239-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8a90/12179056/b2a60115b551/fonc-15-1609239-g003.jpg

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本文引用的文献

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Perforated Calculous Cholecystitis and Incidental Squamous Cell Carcinoma of the Gallbladder-A Complex Relationship with a Difficult Management in the Acute Setting.穿孔性结石性胆囊炎合并胆囊偶然发现的鳞状细胞癌——急性情况下复杂的关系及棘手的处理
Medicina (Kaunas). 2025 Mar 5;61(3):452. doi: 10.3390/medicina61030452.
2
Progress and Challenges in Integrating Nutritional Care into Oncology Practice: Results from a National Survey on Behalf of the NutriOnc Research Group.将营养护理纳入肿瘤学实践的进展与挑战:代表营养肿瘤研究小组进行的全国性调查结果
Nutrients. 2025 Jan 5;17(1):188. doi: 10.3390/nu17010188.
3
Laparoscopic versus open surgery in treating patients with gallbladder cancer: a systematic review and meta-analysis.
腹腔镜手术与开放手术治疗胆囊癌患者的系统评价和Meta分析
Hepatobiliary Surg Nutr. 2024 Jun 1;13(3):444-459. doi: 10.21037/hbsn-22-597. Epub 2023 Aug 7.
4
New trends in diagnosis and management of gallbladder carcinoma.胆囊癌诊断与治疗的新趋势
World J Gastrointest Oncol. 2024 Jan 15;16(1):13-29. doi: 10.4251/wjgo.v16.i1.13.
5
Assessing the Quality of Long-Term Stored Tissues in Formalin and in Paraffin-Embedded Blocks for Histopathological Analysis.评估用于组织病理学分析的长期保存在福尔马林和石蜡包埋块中的组织质量。
J Microsc Ultrastruct. 2022 Feb 4;10(1):23-29. doi: 10.4103/JMAU.JMAU_53_20. eCollection 2022 Jan-Mar.
6
Degree of biliary tract violation during treatment of gallbladder adenocarcinoma is independently associated with development of peritoneal carcinomatosis.在胆囊腺癌治疗过程中胆道侵犯的程度与腹膜癌病的发展独立相关。
J Surg Oncol. 2021 Sep;124(4):581-588. doi: 10.1002/jso.26569. Epub 2021 Jun 11.
7
Benefits and Limitations of a Multidisciplinary Approach in Cancer Patient Management.癌症患者管理中多学科方法的益处与局限性
Cancer Manag Res. 2020 Sep 30;12:9363-9374. doi: 10.2147/CMAR.S220976. eCollection 2020.
8
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Surgery. 2017 Mar;161(3):618-627. doi: 10.1016/j.surg.2016.08.007. Epub 2016 Oct 13.
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Clin Epidemiol. 2014 Mar 7;6:99-109. doi: 10.2147/CLEP.S37357. eCollection 2014.
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J Visc Surg. 2013 Sep;150(4):277-84. doi: 10.1016/j.jviscsurg.2013.03.006. Epub 2013 May 9.