Cai Xue, Li Meitong, Tao Rui, Yun Xinyu, Yang Xinyu, Sun Jiayue, Wei Chuangyu
Heilongjiang Key Laboratory of Photoelectric Functional Materials, College of Chemistry and Chemical Engineering, Mudanjiang Normal University Mudanjiang 157011 P. R. China
RSC Adv. 2025 Jun 23;15(26):21190-21198. doi: 10.1039/d5ra00178a. eCollection 2025 Jun 16.
The increasing threat of pharmaceutical pollution to public health and the environment is a critical issue. This research endeavors to tackle the challenge by developing an advanced electrochemical sensor for the accurate detection of acetaminophen (APAP). A highly sensitive electrochemical sensor, based on a porphyrin polymer, was designed for this purpose. The study shows that the bimetallic structure of the polymer significantly enhances the sensing efficiency of micropollutants. By analyzing its electrochemical properties, the sensor achieved an impressive detection limit of 0.46 μM for APAP, with a linear detection range from 4 to 1000 μM. The sensor also demonstrated strong anti-interference capabilities, along with high reproducibility and stability. Furthermore, it exhibited excellent performance in analyzing actual samples. Compared with single-metal polymer materials, bimetallic polymer materials exhibit the lowest charge transfer resistance, rapid electron transfer rates, and large electrochemical active areas, thereby enabling superior sensing capabilities.
制药污染对公众健康和环境构成的威胁日益增加，这是一个关键问题。本研究致力于通过开发一种先进的电化学传感器来应对这一挑战，以准确检测对乙酰氨基酚（APAP）。为此设计了一种基于卟啉聚合物的高灵敏度电化学传感器。研究表明，该聚合物的双金属结构显著提高了对微污染物的传感效率。通过分析其电化学性质，该传感器对APAP的检测限低至0.46 μM，线性检测范围为4至1000 μM。该传感器还表现出强大的抗干扰能力，以及高重现性和稳定性。此外，它在分析实际样品时表现出色。与单金属聚合物材料相比，双金属聚合物材料具有最低的电荷转移电阻、快速的电子转移速率和较大的电化学活性面积，从而具有卓越的传感能力。
