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衰老的卵巢依靠着巨大的多核细胞。

The aging ovary stands on the shoulders of giant multinucleated cells.

作者信息

Ahmed Avery A, Pangas Stephanie A

机构信息

Department of Pathology & Immunology, Baylor College of Medicine, Houston, Texas, United States of America.

Graduate Program in Development, Disease Models & Therapeutics, Baylor College of Medicine, Houston, Texas, United States of America.

出版信息

PLoS Biol. 2025 Jun 24;23(6):e3003216. doi: 10.1371/journal.pbio.3003216. eCollection 2025 Jun.

Abstract

Reproductive aging is associated with declining fertility and increasing inflammation, though these events are not well understood. An exciting new study in PLOS Biology utilizes cutting-edge technologies to characterize the role of multinucleated giant cells in ovarian aging.

摘要

生殖衰老与生育能力下降和炎症增加有关,尽管这些现象尚未得到充分了解。《公共科学图书馆·生物学》上一项令人兴奋的新研究利用前沿技术来描述多核巨细胞在卵巢衰老中的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bc13/12187170/9478e097a35e/pbio.3003216.g001.jpg

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