Di Bella Santina, Gambino Delia, Foti Maria, Orlandella Bianca Maria, Fisichella Vittorio, Gucciardi Francesca, Mira Francesco, Grasso Rosario, Spena Maria Teresa, Purpari Giuseppa, Guercio Annalisa
Istituto Zooprofilattico Sperimentale della Sicilia, 90129 Palermo, Italy.
Dipartimento di Scienze Veterinarie, Università degli Studi di Messina, 98168 Messina, Italy.
Vet Sci. 2025 May 25;12(6):516. doi: 10.3390/vetsci12060516.
Bats (order Chiroptera) are increasingly recognized as important reservoirs and potential vectors of pathogenic and antimicrobial-resistant bacteria (ARB), with potential implications for human, animal, and environmental health. This study aimed to assess the presence and antimicrobial resistance profiles of bacterial isolates from bat populations in Sicily, an area for which data are currently limited. A total of 132 samples (120 rectal swabs and 12 guano samples) were collected at four sites in the provinces of Catania, Siracusa, and Ragusa. Bacteriological analysis yielded 213 isolates, including 161 Gram-negative and 52 Gram-positive strains, representing 55 different species. Among Gram-negative isolates, , , and were most frequently detected, while and were predominant among Gram-positive bacteria. Antimicrobial susceptibility testing revealed high resistance rates to colistin, amoxicillin, and ampicillin in Gram-negative strains, and to oxacillin, ceftazidime, and lincomycin in Gram-positive strains. Notably, 84.5% of isolates exhibited multidrug resistance. These findings highlight the potential role of bats as reservoirs of ARB and underline the importance of ongoing monitoring within a One Health framework to mitigate risks to public and animal health.
蝙蝠（翼手目）越来越被认为是致病性和抗菌药物耐药性细菌（ARB）的重要宿主及潜在传播媒介，对人类、动物和环境健康具有潜在影响。本研究旨在评估西西里岛蝙蝠种群中细菌分离株的存在情况及其抗菌药物耐药性概况，该地区目前数据有限。在卡塔尼亚省、锡拉库萨省和拉古萨省的四个地点共采集了132份样本（120份直肠拭子和12份粪便样本）。细菌学分析得到213株分离株，包括161株革兰氏阴性菌和52株革兰氏阳性菌，代表55个不同物种。在革兰氏阴性分离株中，最常检测到的是 、 和 ，而在革兰氏阳性菌中 和 占主导地位。抗菌药物敏感性测试显示，革兰氏阴性菌株对黏菌素、阿莫西林和氨苄西林耐药率高，革兰氏阳性菌株对苯唑西林、头孢他啶和林可霉素耐药率高。值得注意的是，84.5%的分离株表现出多重耐药性。这些发现凸显了蝙蝠作为ARB宿主的潜在作用，并强调了在“同一健康”框架内持续监测以降低对公众和动物健康风险的重要性。
