Monsour Robert, Seo Angie, Wilcox Nicholas, Fradley Michael G
Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Thalheimer Center for Cardio-Oncology, Division of Cardiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Curr Cardiol Rep. 2025 Jun 25;27(1):103. doi: 10.1007/s11886-025-02261-4.
Atrial arrhythmias are an increasingly recognized cardiovascular issue for cancer patients and can lead to increased morbidity and mortality independent of the oncologic prognosis. This review highlights the epidemiology of atrial arrhythmias in cancer patients including risk factors and arrhythmogenic cancer treatments as well as the current state of knowledge regarding the prevention and treatment of atrial arrhythmias in this population.
There appears to be bidirectional risk of atrial arrhythmias and cancer, with increased rates of atrial fibrillation identified in cancer patients but also increased cancer in patients with know atrial fibrillation. Moreover, as the cancer treatment landscape has continued to evolve, many novel treatments have been shown to be arrhythmogenic. Currently, the recommendations for the prevention and treatment of cancer associated arrhythmias are the same as the general population. Atrial arrhythmias are common in cancer patients due to multiple factors including shared risk factors and the cancer treatments themselves. Additional research is essential to better understand risk and also to provide cancer-specific recommendations for the prophylaxis and management of atrial arrhythmias and their associated thromboembolic complications.
房性心律失常是癌症患者中一个日益受到认可的心血管问题，可导致发病率和死亡率增加，且与肿瘤预后无关。本综述重点介绍了癌症患者房性心律失常的流行病学，包括危险因素和致心律失常的癌症治疗方法，以及关于该人群房性心律失常预防和治疗的当前知识状态。
房性心律失常与癌症似乎存在双向风险，癌症患者中房颤发生率增加，而已知房颤患者患癌风险也增加。此外，随着癌症治疗格局不断演变，许多新型治疗方法已被证明具有致心律失常性。目前，癌症相关性心律失常的预防和治疗建议与普通人群相同。由于多种因素，包括共同的危险因素和癌症治疗本身，房性心律失常在癌症患者中很常见。进一步的研究对于更好地理解风险以及为房性心律失常及其相关血栓栓塞并发症的预防和管理提供针对癌症的建议至关重要。
