Ferreira Juliana Carvalho, Pereira Adriano José, Cavalcanti Alexandre Biasi, Nassar Junior Antonio Paulo, Serpa Neto Ary, Besen Bruno Adler Maccagnan Pinheiro, Tomazini Bruno Martins, Teixeira Cassiano, Dal-Pizzol Felipe, Bozza Fernando Augusto, Zampieri Fernando Godinho, Machado Flávia Ribeiro, Westphal Glauco Adrieno, Maia Israel Silva, Taniguchi Leandro Utino, Azevedo Luciano Cesar Pontes, Soares Marcio, Ranzani Otavio, Mendes Pedro Vitale, Moraes Rafael Barberena, Rosa Regis Goulart, Biondi Rodrigo Santos, Lobo Suzana Margarete, Lisboa Thiago Costa, Veiga Viviane Cordeiro, Nedel Wagner Luis, Salluh Jorge Ibrain Figueira, Japiassú André Miguel, Pinheiro Bruno do Valle, Righy Cássia, Grion Cíntia Magalhães Carvalho, Costa Eduardo Leite Vieira, Ramos Fernando José da Silva, Freitas Flávio Geraldo Rezende de, Ramos João Gabriel Rosa, Malbouisson Luiz Marcelo Sá, Boniatti Márcio Manozzo, Kurtz Pedro, Roepke Roberta Muriel Longo, Corrêa Thiago Domingos, Nobre Júnior Vandack Alencar
Division of Pulmonology, Instituto do Coração, Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo - São Paulo (SP), Brazil.
Brazilian Research in Intensive Care Network (BRICNet) - São Paulo (SP), Brazil.
Crit Care Sci. 2025 Jun 20;37:e20250284. doi: 10.62675/2965-2774.20250284. eCollection 2025.
Critical illnesses such as sepsis and acute respiratory distress syndrome lead to millions of deaths globally, with a higher burden in low- and middle-income countries. Conducting multicentric clinical studies is essential to help minimize the burden of critical illnesses, particularly in areas where their impact is greater. However, conducting large-scale multicentric studies is challenging, and most large multicentric studies in critical care are from high-income countries, which limits their relevance in other contexts. This highlights the need for collaborative research networks in low- and middle-income countries to better address local needs. The Brazilian Research in Intensive Care Network (BRICNet) was created by a group of intensivists and researchers in 2007 and is dedicated to being the leading organization in Brazil for conducting collaborative clinical research to improve care for critically ill patients. BRICNet focuses on investigator-initiated and collaborative studies relevant to global intensive care, with a special emphasis on Brazilian context. Its mission includes advancing research methodology, scientific writing, and conducting large-scale multicenter studies to fill knowledge gaps in critical care. Since its creation, the network has published 71 articles, including 15 randomized controlled trials and 14 observational studies, many of them in collaboration with major Brazilian institutions and international networks. This review aims to critically assess the achievements of BRICNet, highlighting its high-impact publications, international partnerships, and capacity building, which have significantly contributed to the field of intensive care. Looking ahead, we also identify barriers and solutions for sustainable growth.
脓毒症和急性呼吸窘迫综合征等危重症在全球导致数百万人死亡，在低收入和中等收入国家的负担更重。开展多中心临床研究对于帮助减轻危重症负担至关重要，尤其是在其影响较大的地区。然而，开展大规模多中心研究具有挑战性，重症监护领域的大多数大型多中心研究都来自高收入国家，这限制了这些研究在其他背景下的相关性。这凸显了低收入和中等收入国家建立合作研究网络以更好地满足当地需求的必要性。巴西重症监护研究网络（BRICNet）由一群重症监护医生和研究人员于2007年创建，致力于成为巴西开展合作临床研究以改善危重症患者护理的领先组织。BRICNet专注于与全球重症监护相关的研究者发起的合作研究，特别强调巴西的背景。其使命包括推进研究方法、科学写作以及开展大规模多中心研究，以填补重症监护领域的知识空白。自成立以来，该网络已发表71篇文章，包括15项随机对照试验和14项观察性研究，其中许多是与巴西主要机构和国际网络合作发表的。本综述旨在批判性地评估BRICNet的成就，突出其高影响力的出版物、国际伙伴关系和能力建设，这些都对重症监护领域做出了重大贡献。展望未来，我们还确定了可持续发展的障碍和解决方案。
