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质疑腰大肌测量的作用:对主动脉修复术后结果的预测价值有限

Questioning the Role of Psoas Measurements: Limited Predictive Value for Outcomes After Aortic Repair.

作者信息

Halman Joanna, Szydłowska Klaudia, Znaniecki Łukasz, Wojciechowski Jacek

机构信息

Department of Vascular Surgery, University Clinical Center Gdańsk, Medical University of Gdańsk, 80-210 Gdańsk, Poland.

Scientific Circle of Neurotraumatology, Medical University of Gdańsk, 80-210 Gdańsk, Poland.

出版信息

J Clin Med. 2025 Jun 13;14(12):4227. doi: 10.3390/jcm14124227.

Abstract

Abdominal aortic aneurysm (AAA) repair is a prophylactic intervention aimed at preventing rupture. As the population ages, surgical decision-making becomes increasingly complex, especially in older and frailer patients. Imaging biomarkers, such as psoas muscle area (PMA) and density (PMD), have been proposed as surrogates for frailty and potential predictors of surgical outcomes. However, their clinical utility remains uncertain. : In this retrospective, single-center study, we evaluated 199 patients who underwent elective AAA repair between 2015 and 2019. Preoperative computed tomography angiography (CTA) was used to measure PMA and PMD at the level of the third lumbar vertebra. Lean psoas muscle area (LPMA) was calculated as the product of PMA and PMD. Sarcopenia was defined as the lowest tertile of each measurement. Outcomes were assessed using Fisher's exact test, Kaplan-Meier survival analysis, and logistic regression. : No significant associations were found between PMA, PMD, or LPMA and early or late postoperative complications or mortality. : Psoas muscle indices, measured on routine CTA scans, do not reliably predict postoperative outcomes in AAA patients. These findings suggest that further studies integrating broader clinical and functional assessments are needed to improve risk stratification and inform preoperative decision-making in this patient population.

摘要

腹主动脉瘤(AAA)修复术是一种旨在预防破裂的预防性干预措施。随着人口老龄化,手术决策变得越来越复杂,尤其是在老年和体弱患者中。诸如腰大肌面积(PMA)和密度(PMD)等影像学生物标志物已被提议作为虚弱的替代指标和手术结果的潜在预测指标。然而,它们的临床实用性仍不确定。在这项回顾性单中心研究中,我们评估了199例在2015年至2019年间接受择期AAA修复术的患者。术前计算机断层扫描血管造影(CTA)用于测量第三腰椎水平的PMA和PMD。瘦腰大肌面积(LPMA)通过PMA和PMD的乘积计算得出。肌肉减少症定义为每项测量值的最低三分位数。采用Fisher精确检验、Kaplan-Meier生存分析和逻辑回归评估结果。未发现PMA、PMD或LPMA与术后早期或晚期并发症或死亡率之间存在显著关联。在常规CTA扫描上测量的腰大肌指数不能可靠地预测AAA患者的术后结果。这些发现表明,需要进一步开展整合更广泛临床和功能评估的研究,以改善风险分层并为该患者群体的术前决策提供依据。

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