Chen Qiang, Liu Feng, Zhang LingLing, Jin Yang, Huang Haibin
Department of Neurosurgery, Nantong Third People's Hospital, Affiliated Nantong Hospital 3 of Nantong University, Nantong, Jiangsu, China.
Department of Neurosurgery, Dongtai People's Hospital, Dongtai, Jiangsu, China.
Front Cardiovasc Med. 2025 Jun 11;12:1361273. doi: 10.3389/fcvm.2025.1361273. eCollection 2025.
The present study aimed to assess knowledge, attitudes, and practices (KAP) regarding the prevention of intracerebral hemorrhage among hypertensive patients and medication adherence to hypertension.
We conducted a cross-sectional study at the Third People's Hospital of Nantong City between November 4, 2023 and December 4, 2023. Demographic information, KAP and medication adherence scores were collected using an online questionnaire.
Totally 600 valid questionnaires were analyzed. Among these, 443 participants (73.83%) were female, with a mean age of 62.95 ± 15.07 years. The mean scores for knowledge, attitude, practice, and medication adherence were 13.93 ± 2.88, 32.10 ± 3.22, 25.53 ± 3.44, and 3.12 ± 1.85, respectively. Only 3.50% had high medication compliance to hypertension. Multivariate analyses revealed that uncertain about family history of hypertensive intracerebral hemorrhage [OR = 0.378, 95%CI: (0.218-0.656); = 0.001], no smoking [OR = 4.603, 95%CI: (1.954-10.845); < 0.001], and no alcohol consumption [OR = 3.522, 95%CI: (1.764-7.033); < 0.001] were independently associated with proactive practice. Structural equation modeling (SEM) results revealed direct effects between knowledge and attitude ( = 0.999, < 0.001), knowledge and practice ( = 1.103, < 0.001), as well as attitude and practice ( = 0.452, < 0.001).
Hypertensive patients demonstrated sufficient knowledge, positive attitudes, and inactive practices towards preventing intracerebral hemorrhage, coupled with poor medication adherence to hypertension. Developing targeted interventions to address these gaps and promoting a holistic approach is crucial to improving overall patient outcomes in clinical practice.
本研究旨在评估高血压患者对脑出血预防的知识、态度和行为(KAP)以及高血压药物治疗依从性。
2023年11月4日至2023年12月4日期间,我们在南通市第三人民医院开展了一项横断面研究。通过在线问卷收集人口统计学信息、KAP和药物治疗依从性得分。
共分析了600份有效问卷。其中,443名参与者(73.83%)为女性,平均年龄为62.95±15.07岁。知识、态度、行为和药物治疗依从性的平均得分分别为13.93±2.88、32.10±3.22、25.53±3.44和3.12±1.85。只有3.50%的患者对高血压药物治疗依从性高。多因素分析显示,对高血压脑出血家族史不确定[比值比(OR)=0.378,95%置信区间(CI):(0.218 - 0.656);P = 0.001]、不吸烟[OR = 4.603,95%CI:(1.954 - 10.845);P < 0.001]以及不饮酒[OR = 3.522,95%CI:(1.764 - 7.033);P < 0.001]与积极行为独立相关。结构方程模型(SEM)结果显示知识与态度之间存在直接效应(P = 0.999,P < 0.001)、知识与行为之间存在直接效应(P =