Yang Sun-Gen, Wang Wen-Fu, Tung Yu-Chun, Huang Shang-Chien, Chang Ming-Che, Huang Ling-Chun, Yang Yuan-Han, Jhang Kai-Ming
Department of Medical Education, Changhua Christian Hospital, Changhua, Taiwan.
Department of Neurology, Changhua Christian Hospital, Changhua, Taiwan.
Front Med (Lausanne). 2025 Jun 11;12:1540608. doi: 10.3389/fmed.2025.1540608. eCollection 2025.
This study aimed to evaluate the effectiveness of a 16-week video-based multiple training modality (MTM) program for dementia patients in Community Service Centers for Dementia (CSCDs) in Taiwan.
Cluster Randomized controlled trial.
A total of 16 CSCDs across four counties in Taiwan.
A total of 207 dementia patients and their caregivers, randomly clustered and assigned to an intervention group or a control group.
The intervention group received a 16-week video-based MTM program including dynamic physical exercises and creative activities. The control group continued with regular activities at the CSCDs.
Outcomes measured were behavioral and psychological symptoms of dementia (BPSD) using the Neuropsychiatric Inventory Questionnaire (NPI-Q), caregiver burden using the Zarit's Burden Interview (ZBI), and caregiver depression using the Center for Epidemiologic Studies Depression Scale (CES-D). These were assessed at baseline and post-intervention.
The intervention group showed a significant reduction in appetite/eating distress compared to the control group (change in NPI scores: -0.2 vs. 0, = 0.026). While there was a trend toward reduced caregiver burden, the results were not statistically significant (change in ZBI scores: -3.1 vs. -1.2, = 0.306). No significant changes were observed in overall BPSD severity or caregiver depression.
The video-based MTM program showed potential in improving specific neuropsychological symptoms, especially appetite/eating distress, in dementia patients. The program's ease of implementation suggests it could be expanded across CSCDs in Taiwan, with a recommendation for refinement to better support caregivers.
本研究旨在评估一项为期16周的基于视频的多模式训练(MTM)计划对台湾失智症社区服务中心(CSCD)失智症患者的有效性。
整群随机对照试验。
台湾四个县的16个CSCD。
共207名失智症患者及其照护者,随机分组并分配到干预组或对照组。
干预组接受为期16周的基于视频的MTM计划,包括动态体育锻炼和创意活动。对照组继续在CSCD进行常规活动。
使用神经精神科问卷(NPI-Q)测量失智症的行为和心理症状(BPSD),使用Zarit负担访谈量表(ZBI)测量照护者负担,使用流行病学研究中心抑郁量表(CES-D)测量照护者抑郁。在基线和干预后进行评估。
与对照组相比,干预组的食欲/进食困扰显著减少(NPI评分变化:-0.2对0,P = 0.026)。虽然照护者负担有减轻趋势,但结果无统计学意义(ZBI评分变化:-3.1对-1.2,P = 0.306)。总体BPSD严重程度或照护者抑郁无显著变化。
基于视频的MTM计划在改善失智症患者的特定神经心理症状,尤其是食欲/进食困扰方面显示出潜力。该计划易于实施,表明可在台湾的CSCD中推广,并建议进行改进以更好地支持照护者。