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我们在三级医疗中心使用探针驱动起搏导线(SDL)进行左束支区域起搏(LBBAP)的初步经验。

Our Initial Experience of Left Bundle Branch Area Pacing (LBBAP) With Stylet-Driven Pacing Leads (SDL) in a Tertiary Care Center.

作者信息

Kumar Goutam, Chandan Chandrabhanu, T K Nithyapriya, Prasad Ravi V

机构信息

Department of Cardiology, Indira Gandhi Institute of Medical Sciences, Patna, IND.

出版信息

Cureus. 2025 May 26;17(5):e84845. doi: 10.7759/cureus.84845. eCollection 2025 May.

DOI:10.7759/cureus.84845
PMID:40568258
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12189849/
Abstract

Background The use of left bundle branch area pacing (LBBAP) as a substitute for conduction system pacing (CSP) is becoming increasingly popular. Thus, this study was performed to evaluate the feasibility, safety, and outcomes of LBBAP with stylet-driven pacing leads (SDL) in a tertiary care center in Eastern India. Materials and methods This single-center, retrospective study was conducted at the Department of Cardiology, Indira Gandhi Institute of Medical Sciences (IGIMS), Patna, Bihar, India. The study included data from 20 patients over one year, i.e., from December 2023 to December 2024. The procedure-related characteristics included fluoroscopy exposure duration, doses, and patterns of electrocardiograms (ECG) and intracardiac electrograms (EGM) that were documented during implantation. The Institutional Ethics Committee (IEC), IGIMS, Patna, Bihar, India, has granted ethical approval (approval no. 291/IEC/IGIMS/2025, dated January 9, 2025). Results Implant success was observed in 18 (90%) patients. Significant differences were observed in bundle branch block and pacing indications with p-values <0.001 and 0.002, respectively. It was noted that a highly statistically significant result was obtained when unipolar impedance and bipolar impedance were compared, with a p-value of 0.002. Conclusion Our study found that permanent LBBAP is a viable physiological pacing method with a 90% success rate. Moreover, septal perforation complications were not noted. Among the limitations of the study were the small number of patients, which might affect the efficiency of the results, and the shorter duration of time. Additionally, the study was retrospective; thus, similar records of some parameters were difficult to find.

摘要

背景 左束支区域起搏(LBBAP)作为传导系统起搏(CSP)的替代方法正变得越来越流行。因此,本研究旨在评估在印度东部一家三级医疗中心使用带芯导线驱动起搏电极(SDL)进行LBBAP的可行性、安全性和结果。

材料和方法 这项单中心回顾性研究在印度比哈尔邦巴特那英迪拉·甘地医学科学研究所(IGIMS)心脏病学系进行。该研究纳入了2023年12月至2024年12月这一年期间20例患者的数据。与手术相关的特征包括透视暴露持续时间、剂量以及植入过程中记录的心电图(ECG)和心内心电图(EGM)模式。印度比哈尔邦巴特那IGIMS的机构伦理委员会(IEC)已给予伦理批准(批准号291/IEC/IGIMS/2025,日期为2025年1月9日)。

结果 18例(90%)患者植入成功。在束支传导阻滞和起搏指征方面观察到显著差异,p值分别<0.001和0.002。注意到比较单极阻抗和双极阻抗时获得了高度统计学显著结果,p值为0.002。

结论 我们的研究发现永久性LBBAP是一种可行的生理性起搏方法,成功率为90%。此外,未发现间隔穿孔并发症。该研究的局限性包括患者数量少,这可能影响结果的有效性,以及时间持续较短。此外,该研究是回顾性的;因此,一些参数的类似记录难以找到。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9490/12189849/a8e27a27532f/cureus-0017-00000084845-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9490/12189849/a8e27a27532f/cureus-0017-00000084845-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9490/12189849/a8e27a27532f/cureus-0017-00000084845-i01.jpg

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Left Bundle Branch Pacing vs Left Ventricular Septal Pacing vs Biventricular Pacing for Cardiac Resynchronization Therapy.
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