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尽管2018 - 2023年期间在14个受总统紧急艾滋病救援计划(PEPFAR)支持的撒哈拉以南非洲国家,暴力事件后服务提供有所改善,但暴露后预防措施的完成情况仍较差。

Poor post-exposure prophylaxis completion despite improvements in post-violence service delivery in 14 PEPFAR-supported sub-Saharan African countries, 2018-2023.

作者信息

Kanagasabai Udhayashankar, Davis Stephanie M, Thorsen Viva, Rowlinson Emily, Laterra Anne, Hegle Jennifer, Angumua Carrine, Ekra Alexandre, Mpingulu Minlangu, Getahun Meklit, Sida Fikirte, Mndzebele Phumzile, Kambona Caroline, Ramphalla Puleng, Mtingwi Eunice, Msungama Wezi, Duffy Meghan, Adewumi Bukola, Olotu Ezeomu, Sebeza Jackson, Kitalile Jane, Apondi Rose, Muleya Carlos, Cain Meagan

机构信息

HIV Prevention Branch, Division of Global HIV and Tuberculosis, CDC, Atlanta, Georgia, USA.

Division of Global HIV and Tuberculosis, CDC, Yaounde, Cameroon.

出版信息

J Int AIDS Soc. 2025 Jun;28 Suppl 1(Suppl 1):e26469. doi: 10.1002/jia2.26469.

DOI:10.1002/jia2.26469
PMID:40569898
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12231646/
Abstract

INTRODUCTION

Sexual violence (SV) affects millions globally and has a well-documented bidirectional association with HIV. Post-exposure prophylaxis (PEP) is a critical, yet often underutilized, HIV prevention tool in post-SV care. Despite its potential impact to reduce HIV transmission, SV care remains an overlooked service delivery point for HIV prevention. The U.S. Centers for Disease Control and Prevention (CDC), as part of the President's Emergency Plan for AIDS Relief (PEPFAR), supports PEP provision within broader post-violence care (PVC) services. Understanding PEP utilization is crucial for optimizing service delivery and HIV prevention efforts.

METHODS

Using Monitoring Evaluation and Reporting data from fiscal years 2018-2023, we conducted a descriptive analysis of clients who received PVC and SV services through CDC-supported programming in 14 sub-Saharan African countries.

RESULTS

From 2018 to 2023, the annual number of clients receiving any PVC, and specifically SV, services increased by 233% (in 2018, n = 206,764; in 2023, n = 689,349) and 163% (in 2018, n = 42,848; in 2023, n = 112,838), respectively. Fewer than half of SV clients completed PEP (38% in 2018, n = 16,103; 31% in 2023, n = 35,118). Across all years combined, most SV clients (female: 185,414; male: 59,618) were aged 15-19 years. The age band and sex with the lowest proportion of clients completing PEP were males aged 15-19 (4%, n = 2296).

CONCLUSIONS

The findings underscore a critical gap between the scaling of SV services and the completion of PEP within violence response programmes. Innovative implementation science approaches may help to identify and address barriers inhibiting effective PEP delivery and uptake within PVC service delivery programmes. Enhancing PEP uptake and completion can support mitigating the bidirectional relationship between violence and HIV acquisition, particularly among vulnerable populations like adolescents and young adults. Low PEP coverage also reflects missed opportunities, particularly among adolescent girls and young women, who experience disproportionate rates of HIV acquisition.

摘要

引言

性暴力在全球范围内影响着数百万人,并且与艾滋病毒存在着有据可查的双向关联。暴露后预防(PEP)是性暴力后护理中一项关键但经常未得到充分利用的艾滋病毒预防工具。尽管其对减少艾滋病毒传播具有潜在影响,但性暴力护理仍然是艾滋病毒预防中一个被忽视的服务提供点。作为总统艾滋病紧急救援计划(PEPFAR)的一部分,美国疾病控制与预防中心(CDC)支持在更广泛的暴力后护理(PVC)服务中提供暴露后预防。了解暴露后预防的使用情况对于优化服务提供和艾滋病毒预防工作至关重要。

方法

利用2018 - 2023财年的监测评估和报告数据,我们对通过疾病预防控制中心支持的项目在14个撒哈拉以南非洲国家接受暴力后护理和性暴力服务的客户进行了描述性分析。

结果

从2018年到2023年,接受任何暴力后护理服务,特别是性暴力服务的客户年度数量分别增加了233%(2018年,n = 206,764;2023年,n = 689,349)和163%(2018年,n = 42,848;2023年,n = 112,838)。完成暴露后预防的性暴力客户不到一半(2018年为38%,n = 16,103;2023年为31%,n = 35,118)。在所有年份中,大多数性暴力客户(女性:185,414;男性:59,618)年龄在15 - 19岁之间。完成暴露后预防比例最低的年龄组和性别是15 - 19岁的男性(4%,n = 2296)。

结论

研究结果强调了性暴力服务的扩大与暴力应对项目中暴露后预防的完成之间存在关键差距。创新的实施科学方法可能有助于识别和解决阻碍在暴力后护理服务提供项目中有效提供和接受暴露后预防的障碍。提高暴露后预防的接受度和完成率有助于减轻暴力与艾滋病毒感染之间的双向关系,特别是在青少年和年轻人等弱势群体中。暴露后预防覆盖率低也反映了错失的机会,特别是在艾滋病毒感染率不成比例的少女和年轻女性中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0731/12231646/d30299cbcdcd/JIA2-28-e26469-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0731/12231646/d30299cbcdcd/JIA2-28-e26469-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0731/12231646/d30299cbcdcd/JIA2-28-e26469-g001.jpg

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本文引用的文献

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Child Abuse Negl. 2024 Apr;150:106541. doi: 10.1016/j.chiabu.2023.106541. Epub 2023 Dec 19.
2
Psychosocial interventions for survivors of rape and sexual assault experienced during adulthood.成年期经历强奸和性侵犯的幸存者的心理社会干预。
Cochrane Database Syst Rev. 2023 Oct 5;10(10):CD013456. doi: 10.1002/14651858.CD013456.pub2.
3
Understanding Gender-Based Violence Service Delivery in CDC-Supported Health Facilities: 15 Sub-Saharan African Countries, 2017-2021.
了解疾控中心支持的卫生机构中基于性别的暴力服务提供情况:2017-2021 年,15 个撒哈拉以南非洲国家。
AIDS Educ Prev. 2023 Jul;35:39-51. doi: 10.1521/aeap.2023.35.suppA.39.
4
Association between lifetime sexual violence victimization and selected health conditions and risk behaviors among 13-24-year-olds in Lesotho: Results from the Violence Against Children and Youth Survey (VACS), 2018.莱索托 13-24 岁青少年一生中遭受性暴力侵害与某些健康状况和风险行为之间的关联:暴力侵害儿童和青少年调查(VACS)的结果,2018 年。
Child Abuse Negl. 2022 Dec;134:105916. doi: 10.1016/j.chiabu.2022.105916. Epub 2022 Oct 7.
5
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BMC Health Serv Res. 2022 Jul 29;22(1):962. doi: 10.1186/s12913-022-08373-9.
6
Changes in prevalence of violence and risk factors for violence and HIV among children and young people in Kenya: a comparison of the 2010 and 2019 Kenya Violence Against Children and Youth Surveys.肯尼亚儿童和青少年中暴力流行率变化以及暴力和艾滋病毒风险因素:2010 年和 2019 年肯尼亚暴力侵害儿童和青少年调查比较。
Lancet Glob Health. 2022 Jan;10(1):e124-e133. doi: 10.1016/S2214-109X(21)00457-5. Epub 2021 Nov 22.
7
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9
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BMC Public Health. 2019 Jul 8;19(1):897. doi: 10.1186/s12889-019-7192-4.
10
Sexual assault victimization and psychopathology: A review and meta-analysis.性侵犯受害经历与精神病理学:一项综述与荟萃分析。
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