Osnes M, Myren J, Lotveit T, Swensen T
Scand J Gastroenterol. 1977;12(3):347-51. doi: 10.3109/00365527709180939.
In a consecutive series of 174 patients the biliary and pancreatic ducts were demonstrated by endoscopic retrograde cholangio-pancreatography (ERCP). In 84 patients with normal duct systems, juxtapapillary diverticula were found in 5 patients (6%). In 90 cases with ductal abnormalities due to biliary concrements, dilated common bile duct and pancreatitis, diverticula were found in 35 patients (39%). In patients with abnormalities in both duct systems, diverticula were found in 52%, and in patients with changes in one duct system diverticula were found in 33%. The difference in occurrence of diverticula in patients with normal duct systems and pathological duct systems was statistically significant (p less than 0.02). The findings indicate a correlation between juxtapapillary diverticula and pathological changes due to biliary concrements, dilated common bile duct without concrements and pancreatitis.
在连续的174例患者中,通过内镜逆行胰胆管造影(ERCP)显示了胆管和胰管。在84例导管系统正常的患者中,5例(6%)发现了乳头旁憩室。在90例因胆石症、胆总管扩张和胰腺炎导致导管异常的病例中,35例(39%)发现了憩室。在两个导管系统均有异常的患者中,52%发现了憩室,在一个导管系统有改变的患者中,33%发现了憩室。导管系统正常的患者与病理导管系统的患者中憩室发生率的差异具有统计学意义(p<0.02)。这些发现表明乳头旁憩室与胆石症、无结石的胆总管扩张和胰腺炎引起的病理变化之间存在相关性。