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扫描电子显微镜在风湿性心脏病阿绍夫小体特征描述中的应用。

Application of scanning electron microscopy in the characterization of Aschoff nodules in rheumatic heart disease.

作者信息

Chopra P

出版信息

Jpn Heart J. 1985 Jul;26(4):531-8. doi: 10.1536/ihj.26.531.

DOI:10.1536/ihj.26.531
PMID:4057553
Abstract

Aschoff nodules (ANs) in excised atrial appendages from cases of rheumatic heart disease were examined with a scanning electron microscope (SEM). ANs could be identified with ease as nodular, fairly well defined cell aggregates lying in the subendocardium closely apposed to the myocardium. Cells comprising ANs were loosely packed in stacks. They were rectangular, oblong and angulated. The surface of some cells had fine ribbing while others were smooth having occasional blunt projections. SEM observations coupled with the findings of conventional and electron microscopy suggest that cells composing ANs are of mesenchymal origin having characters of epithelioid cells, reticular cells and/or fibroblasts.

摘要

用扫描电子显微镜(SEM)检查风湿性心脏病病例切除的心耳中的阿绍夫小体(ANs)。阿绍夫小体很容易被识别为位于心内膜下与心肌紧密相邻的结节状、边界相当清晰的细胞聚集体。构成阿绍夫小体的细胞松散地堆叠在一起。它们呈长方形、椭圆形和有角形。一些细胞表面有细微的纹理,而另一些则很光滑,偶尔有钝突起。扫描电子显微镜观察结果与传统显微镜和电子显微镜的发现表明,构成阿绍夫小体的细胞起源于间充质,具有上皮样细胞、网状细胞和/或成纤维细胞的特征。

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