Lacsa Jose Eric M
De La Salle University, the Republic of the Philippines.
Int J Cardiol Cardiovasc Risk Prev. 2025 Jun 6;26:200449. doi: 10.1016/j.ijcrp.2025.200449. eCollection 2025 Sep.
Recent data from the United States reveal a rising trend in mortality linked to inflammatory bowel disease (IBD) and cardiovascular disease (CVD), with pronounced disparities across age, sex, race, and geography. This commentary reappropriates those findings within the context of the Philippines and other low- and middle-income countries (LMICs), where chronic inflammation remains underdiagnosed and health systems are ill-equipped to address its cardiovascular consequences. While CVD is already the leading cause of death in the Philippines, the compounding effects of inflammatory disorders like IBD are largely overlooked. Drawing parallels from U.S. patterns, we highlight how rural-urban divides, healthcare inaccessibility, and poor disease surveillance may fuel similar trends in LMICs. We call for integrated screening strategies, improved chronic disease registries, and cross-disciplinary approaches that recognize inflammation as a key driver of cardiovascular risk. The global burden of cardiovascular disease cannot be fully addressed without confronting the silent role of systemic inflammation.
美国最近的数据显示，与炎症性肠病（IBD）和心血管疾病（CVD）相关的死亡率呈上升趋势，在年龄、性别、种族和地域方面存在明显差异。本评论将这些发现置于菲律宾和其他低收入和中等收入国家（LMICs）的背景下重新审视，在这些国家，慢性炎症仍未得到充分诊断，卫生系统也缺乏应对其心血管后果的能力。虽然心血管疾病已经是菲律宾的主要死因，但像炎症性肠病这样的炎症性疾病的复合影响在很大程度上被忽视了。借鉴美国的模式，我们强调城乡差距、医疗服务不可及以及疾病监测不力如何可能在低收入和中等收入国家引发类似趋势。我们呼吁采取综合筛查策略、改进慢性病登记系统以及跨学科方法，将炎症视为心血管风险的关键驱动因素。如果不应对全身性炎症的隐性作用，就无法全面解决全球心血管疾病负担问题。
