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生长迅速的脑膜瘤:一种可能的恶性伪装者?

A meningioma with rapid growth: A possible malignancy imposter?

作者信息

Pan Zhenjiang, Bao Jing, Wei Shepeng

机构信息

Department of Neurosurgery, Shidong Hospital, Shanghai, 200438, China.

Department of Neurosurgery, Shidong Hospital, No. 999, Shiguang Road, Yangpu District, Shanghai, 200438, China.

出版信息

Open Life Sci. 2025 Jun 12;20(1):20251118. doi: 10.1515/biol-2025-1118. eCollection 2025.

DOI:10.1515/biol-2025-1118
PMID:40575728
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12198944/
Abstract

Meningiomas, accounting for approximately 33% of primary central nervous system tumors, are the most prevalent type in this category. Advanced age is frequently viewed as a barrier to surgical intervention, yet recent cases have challenged this perception by demonstrating successful outcomes in elderly patients. This case report aims to illustrate the feasibility and benefits of surgical treatment in older individuals. An 84-year-old patient presented with a newly diagnosed meningioma and underwent surgical tumor removal at age 88. Following a comprehensive preoperative evaluation that excluded significant comorbidities, the procedure utilized advanced surgical techniques and optimized postoperative care to ensure safety and recovery. Pathology revealed a World Health Organization grade 1 fibrous meningioma, confirming its benign nature. The patient tolerated the surgery well and recovered successfully, marking her as the oldest reported individual to undergo such treatment. This case demonstrates that advanced age does not inherently limit tumor growth or preclude surgical intervention. Through meticulous patient assessment and personalized treatment strategies, elderly patients can achieve positive outcomes. It highlights the value of a tailored approach, prioritizing overall health and specific medical needs, and supports proactive surgical management to enhance quality of life and clinical results. This challenges traditional assumptions about age-related restrictions on surgical feasibility.

摘要

脑膜瘤约占原发性中枢神经系统肿瘤的33%,是该类别中最常见的类型。高龄常被视为手术干预的障碍,但最近的病例通过在老年患者中取得成功结果对这一观念提出了挑战。本病例报告旨在说明老年患者手术治疗的可行性和益处。一名84岁患者被诊断出患有新发脑膜瘤,并在88岁时接受了肿瘤切除手术。在全面的术前评估排除了严重合并症后,手术采用了先进的手术技术并优化了术后护理以确保安全和康复。病理显示为世界卫生组织1级纤维性脑膜瘤,证实其良性性质。患者对手术耐受性良好且成功康复,成为接受此类治疗的年龄最大的报告病例。该病例表明,高龄本身并不限制肿瘤生长或排除手术干预。通过细致的患者评估和个性化治疗策略,老年患者可以取得积极的结果。它突出了量身定制方法的价值,优先考虑整体健康和特定医疗需求,并支持积极的手术管理以提高生活质量和临床效果。这对关于与年龄相关的手术可行性限制的传统假设提出了挑战。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e450/12198944/41d37a4ad17f/j_biol-2025-1118-fig005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e450/12198944/48cf44fc95a4/j_biol-2025-1118-fig001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e450/12198944/866ee2f78c4c/j_biol-2025-1118-fig002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e450/12198944/3de38fc0cd9b/j_biol-2025-1118-fig003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e450/12198944/9d3a6f33ce28/j_biol-2025-1118-fig004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e450/12198944/41d37a4ad17f/j_biol-2025-1118-fig005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e450/12198944/48cf44fc95a4/j_biol-2025-1118-fig001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e450/12198944/866ee2f78c4c/j_biol-2025-1118-fig002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e450/12198944/3de38fc0cd9b/j_biol-2025-1118-fig003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e450/12198944/9d3a6f33ce28/j_biol-2025-1118-fig004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e450/12198944/41d37a4ad17f/j_biol-2025-1118-fig005.jpg

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本文引用的文献

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