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虚拟细胞挑战:迈向虚拟细胞的图灵测试。

Virtual Cell Challenge: Toward a Turing test for the virtual cell.

作者信息

Roohani Yusuf H, Hua Tony J, Tung Po-Yuan, Bounds Lexi R, Yu Feiqiao B, Dobin Alexander, Teyssier Noam, Adduri Abhinav, Woodrow Alden, Plosky Brian S, Mehta Reshma, Hsu Benjamin, Sullivan Jeremy, Ricci-Tam Chiara, Li Nianzhen, Kazaks Julia, Gilbert Luke A, Konermann Silvana, Hsu Patrick D, Goodarzi Hani, Burke Dave P

机构信息

Arc Institute, Palo Alto, CA, USA.

Arc Institute, Palo Alto, CA, USA; University of California, San Francisco, San Francisco, CA, USA.

出版信息

Cell. 2025 Jun 26;188(13):3370-3374. doi: 10.1016/j.cell.2025.06.008.

DOI:10.1016/j.cell.2025.06.008
PMID:40578317
Abstract

Virtual cells are an emerging frontier at the intersection of artificial intelligence and biology. A key goal of these cell state models is predicting cellular responses to perturbations. The Virtual Cell Challenge is being established to catalyze progress toward this goal. This recurring and open benchmark competition from the Arc Institute will provide an evaluation framework, purpose-built datasets, and a venue for accelerating model development.

摘要

虚拟细胞是人工智能与生物学交叉领域中一个新兴的前沿领域。这些细胞状态模型的一个关键目标是预测细胞对干扰的反应。正在设立虚拟细胞挑战赛以推动朝着这一目标取得进展。这个来自Arc研究所的定期开放基准竞赛将提供一个评估框架、专门构建的数据集以及一个加速模型开发的平台。

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