猪主要病毒性疾病管理中的全球挑战与进展

Global Challenges and Advancements in the Management of Pivotal Porcine/Swine Viral Diseases.

作者信息

Kwon Taeho, Bae Gyu-Seo, Jeon Eunsu, Kang Philyong, Son Hee Chang, An You Jung, Koo Bon-Sang, Kim Sun-Uk, Lim Kyung-Seob

机构信息

Primate Resources Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Jeonbuk, Republic of Korea.

Futuristic Animal Resource and Research Center, Korea Research Institute of Bioscience and Biotechnology, Ochang, Republic of Korea.

出版信息

In Vivo. 2025 Jul-Aug;39(4):1810-1832. doi: 10.21873/invivo.13982.

Abstract

Porcine/swine viral diseases pose substantial challenges to the global pig industry by affecting animal health and economic stability. This comprehensive review examines four major viral diseases impacting swine populations worldwide: Porcine reproductive and respiratory syndrome (PRRS), African swine fever (ASF), classical swine fever (CSF), and porcine circovirus type 2 (PCV2). We investigated the etiology, epidemiology, clinical signs, and diagnostic methods for each disease, thereby providing an in-depth understanding of their complexities. Additionally, we assessed their global distribution, transmission dynamics, and the economic repercussions they entail. We also discuss current management and control strategies, including vaccination, biosecurity measures, and regulatory policies. Special attention is given to the evolving nature of these diseases, with a focus on emerging strains, new insights into their pathogenesis, and the latest advancements in vaccine development. This review intends to be a valuable resource for veterinarians, researchers, and policymakers, presenting a thorough and current overview of the challenges and developments in managing these swine viral diseases at the international level.

摘要

猪病毒性疾病通过影响动物健康和经济稳定性,给全球养猪业带来了巨大挑战。本综述全面审视了影响全球猪群的四种主要病毒性疾病:猪繁殖与呼吸综合征(PRRS)、非洲猪瘟(ASF)、经典猪瘟(CSF)和猪圆环病毒2型(PCV2)。我们研究了每种疾病的病因、流行病学、临床症状和诊断方法,从而深入了解它们的复杂性。此外,我们评估了它们的全球分布、传播动态以及所带来的经济影响。我们还讨论了当前的管理和控制策略,包括疫苗接种、生物安全措施和监管政策。特别关注这些疾病的不断演变的性质,重点是新兴毒株、对其发病机制的新见解以及疫苗开发的最新进展。本综述旨在为兽医、研究人员和政策制定者提供有价值的资源,全面且及时地概述在国际层面管理这些猪病毒性疾病所面临的挑战和进展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d865/12223619/69d7d2fc3703/in_vivo-39-1815-g0001.jpg

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