Poglazova M N, Verbina N M, Nikitina R N
Mikrobiologiia. 1985 Jul-Aug;54(4):628-33.
The object of this work was to study the effect of sulfochlorantine (SCA), a new disinfecting compound containing chlorine, on Mycobacterium rubrum cells. The sensitivity of the cells to this agent was studied as well as their ultrastructure at the doses 0.01, 0.025, 0.05 and 0.1%. Even at high doses, the cells did not die off immediately when their growth and division stopped. Changes in the ultrastructural organization of the cells depended on the concentration of SCA. The structure of the nucleoid, membranes and ribosomes was damaged. Considerable changes were found in the formation of cross septa. The structure of the cells wall was modified to a lesser degree. The results are consistent with the biochemical data available.
这项工作的目的是研究一种含氯的新型消毒化合物磺氯苯胺（SCA）对红色分枝杆菌细胞的影响。研究了细胞对该试剂的敏感性以及在0.01%、0.025%、0.05%和0.1%剂量下的超微结构。即使在高剂量下，当细胞的生长和分裂停止时，它们也不会立即死亡。细胞超微结构组织的变化取决于SCA的浓度。拟核、膜和核糖体的结构受到破坏。在交叉隔膜的形成中发现了相当大的变化。细胞壁的结构变化较小。这些结果与现有的生化数据一致。
