Nagata Shuji, Sawano Miyuki, Shouji Yuki, Oka Masayuki, Kurata Seiji, Hiraoka Koji, Akiba Jun, Tanoue Shuichi
Department of Radiology, Kurume University School of Medicine, Kurume, Fukuoka, Japan.
Department of Orthopaedics, Kurume University School of Medicine, Kurume, Fukuoka, Japan.
Radiol Case Rep. 2025 Jun 13;20(9):4368-4372. doi: 10.1016/j.radcr.2025.05.062. eCollection 2025 Sep.
Anaplastic large cell lymphoma (ALCL) represents one of the rare types of non-Hodgkin lymphoma. We describe a case of primary bone anaplastic lymphoma kinase (ALK)-positive ALCL presented as a giant extraskeletal mass with extensive coagulation necrosis. There have been only a few case reports detailing radiological imaging of primary bone ALCL with extraskeletal extension and to the best of our knowledge this is the first documented case associating ALCL with coagulation necrosis.
间变性大细胞淋巴瘤(ALCL)是罕见的非霍奇金淋巴瘤类型之一。我们描述了一例原发性骨间变性淋巴瘤激酶(ALK)阳性的ALCL,表现为巨大的骨骼外肿块,并伴有广泛的凝固性坏死。仅有少数病例报告详细描述了原发性骨ALCL伴骨骼外扩展的放射影像学表现,据我们所知,这是第一例记录在案的将ALCL与凝固性坏死相关联的病例。