T2加权磁共振成像联合扩散加权成像用于结肠癌淋巴结检查

T2 magnetic resonance imaging combined with diffusion-weighted imaging for colon cancer lymph nodes.

作者信息

Li Yong-Xia, Cai Sheng-Li, Peng Ming-Yang, Wang Tong-Xing, Geng Wen, Ma Yue-Hu

机构信息

Department of Imaging, Nanjing Pukou District Hospital of Traditional Chinese Medicine, Nanjing 211800, Jiangsu Province, China.

Department of Imaging, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, Jiangsu Province, China.

出版信息

World J Gastrointest Surg. 2025 Jun 27;17(6):103298. doi: 10.4240/wjgs.v17.i6.103298.

DOI:10.4240/wjgs.v17.i6.103298

PMID:40584475

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12188573/

Abstract

BACKGROUND

Colorectal cancer is a malignancy with a high risk of lymph node metastasis and poor prognosis, and thus requires an accurate diagnosis.

AIM

To assess the diagnostic value of combined magnetic resonance T2-weighted imaging (T2WI) and diffusion-weighted imaging (DWI) in colorectal cancer.

METHODS

We included 120 patients with suspected colorectal cancer who underwent magnetic resonance imaging. Surgical pathology was used as the gold standard for comparison. Combined T2WI and DWI showed higher diagnostic efficacy than either of the two methods used individually.

RESULTS

The combined method achieved 94.74% sensitivity, 95.45% specificity, 95.00% accuracy, 94.74% positive predictive value, and 95.45% negative predictive value in qualitative diagnosis. It showed 94.44% sensitivity, 95.00% specificity, 94.74% accuracy, 94.44% positive predictive value, and 95.00% negative predictive value in clinical staging. Finally, it showed 94.74% sensitivity, 94.59% specificity, 94.74% accuracy, 94.74% positive predictive value, and 94.59% negative predictive value in diagnosing lymph node metastasis. These results were highly consistent with that of the gold standard.

CONCLUSION

This study combined T2WI and DWI for accurate diagnosis of colorectal cancer, aiding clinical staging and lymph node metastasis assessment. This approach is promising for clinical application.

摘要

背景

结直肠癌是一种具有高淋巴结转移风险和不良预后的恶性肿瘤，因此需要准确诊断。

目的

评估磁共振T2加权成像（T2WI）和扩散加权成像（DWI）联合应用于结直肠癌的诊断价值。

方法

我们纳入了120例疑似结直肠癌并接受磁共振成像检查的患者。以手术病理作为比较的金标准。T2WI和DWI联合应用显示出比单独使用这两种方法中任何一种更高的诊断效能。

结果

联合方法在定性诊断中灵敏度为94.74%、特异度为95.45%、准确度为95.00%、阳性预测值为94.74%、阴性预测值为95.45%。在临床分期中灵敏度为94.44%、特异度为95.00%、准确度为94.74%、阳性预测值为94.44%、阴性预测值为95.00%。最后，在诊断淋巴结转移方面灵敏度为94.74%、特异度为94.59%、准确度为94.74%、阳性预测值为94.74%、阴性预测值为94.59%。这些结果与金标准的结果高度一致。