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肝癌介入治疗患者的全身并发症及管理策略

Systemic complications and management strategies in liver cancer patients undergoing interventional therapy.

作者信息

Shan Yue-Zhan, Jiao Yan, Guo Hui-Ling, Liu Ya-Hui

机构信息

Department of Gastrointestinal Colorectal Surgery, China-Japan Union Hospital of Jilin University, Changchun 130022, Jilin Province, China.

Department of Hepatobiliary and Pancreatic Surgery, General Surgery Center, The First Hospital of Jilin University, Changchun 130021, Jilin Province, China.

出版信息

World J Gastrointest Surg. 2025 Jun 27;17(6):104883. doi: 10.4240/wjgs.v17.i6.104883.

Abstract

Liver cancer presents unique challenges due to its systemic impact and complex treatment modalities. Patients often experience a range of complications, including cardiovascular, renal, hematological, and metabolic abnormalities, which can significantly affect treatment outcomes and quality of life. This article emphasizes the integration of multidisciplinary strategies and artificial intelligence-driven diagnostics, which have the potential to improve patient outcomes by optimizing early detection and targeted management of these complications. A recent study on 60 liver cancer patients undergoing interventional therapy highlighted the importance of recognizing and managing these complications. This article offers an overview of systemic complications in liver cancer, focusing on pathophysiological mechanisms, risk factors, and strategies to improve care. By addressing gaps in the existing literature and proposing future research directions, it underscores the importance of comprehensive, patient-centered approaches to refine therapeutic strategies.

摘要

由于肝癌具有全身影响和复杂的治疗方式,因此带来了独特的挑战。患者常常会出现一系列并发症,包括心血管、肾脏、血液学和代谢异常,这些并发症会显著影响治疗效果和生活质量。本文强调多学科策略与人工智能驱动诊断的整合,这有可能通过优化这些并发症的早期检测和靶向管理来改善患者预后。最近一项针对60例接受介入治疗的肝癌患者的研究突出了识别和管理这些并发症的重要性。本文概述了肝癌的全身并发症,重点关注病理生理机制、危险因素以及改善护理的策略。通过弥补现有文献中的空白并提出未来的研究方向,它强调了采用全面的、以患者为中心的方法来完善治疗策略的重要性。

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Molecular pathogenesis and systemic therapies for hepatocellular carcinoma.肝细胞癌的分子发病机制和系统治疗。
Nat Cancer. 2022 Apr;3(4):386-401. doi: 10.1038/s43018-022-00357-2. Epub 2022 Apr 28.
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Nutritional therapy for hepatocellular carcinoma.肝细胞癌的营养治疗
World J Gastrointest Oncol. 2021 Oct 15;13(10):1440-1452. doi: 10.4251/wjgo.v13.i10.1440.

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