Xie Ren-Xian, Xing Yi-Xuan, Sun Nian-Zhe
Department of Radiation Oncology, Cancer Hospital of Shantou University Medical College, Shantou 515031, Guangdong Province, China.
Department of Emergency, Xiangya Hospital, Central South University, Changsha 410008, Hunan Province, China.
World J Gastrointest Surg. 2025 Jun 27;17(6):108152. doi: 10.4240/wjgs.v17.i6.108152.
The recent study by Min provides evidence supporting laparoscopic radical resection of colorectal cancer (LRRCC) as a superior surgical approach for elderly patients. Their retrospective analysis of 104 patients demonstrated that LRRCC offers higher therapeutic efficacy, reduced postoperative complications, faster recovery, and attenuated systemic inflammatory responses compared to open surgery. While the study underscores the clinical advantages of minimally invasive techniques, it also highlights critical gaps, such as single-center design and limited long-term follow-up. This editorial contextualizes these findings within the broader literature, emphasizing the role of LRRCC in enhancing postoperative quality of life for elderly patients. We further discuss the implications of inflammatory biomarker modulation, advocate for multidisciplinary care models, and call for prospective trials to validate long-term outcomes.
闵最近的研究提供了证据，支持腹腔镜根治性切除结直肠癌（LRRCC）作为老年患者的一种更优手术方法。他们对104例患者的回顾性分析表明，与开放手术相比，LRRCC具有更高的治疗效果、更少的术后并发症、更快的恢复速度以及减轻的全身炎症反应。虽然该研究强调了微创技术的临床优势，但也突出了一些关键差距，如单中心设计和有限的长期随访。这篇社论将这些发现置于更广泛的文献背景中，强调了LRRCC在提高老年患者术后生活质量方面的作用。我们进一步讨论了炎症生物标志物调节的意义，倡导多学科护理模式，并呼吁进行前瞻性试验以验证长期结果。
