Malook Said, Parvaiz Hassan, Sahani Javeria, Arbi Muhammad, Ur Rehman Wajeeh, Alam Muniba, Laiq Mahpara, Mehboob Rabia
Emergency Medicine, Peshawar General Hospital, Peshawar, PAK.
Medicine, Abdullah Hospital, Lalamusa, PAK.
Cureus. 2025 May 28;17(5):e84958. doi: 10.7759/cureus.84958. eCollection 2025 May.
Introduction Diabetes is a major cause of worldwide morbidity and mortality. Diet and medication non-adherence are common among individuals with diabetes, making glycemic control difficult to attain. Objective To assess the effect of a personalized health intervention on treatment compliance and clinical outcomes in patients with diabetes mellitus (DM). Methodology This quasi-experimental study was conducted at the Aga Khan University Hospital, Karachi, from January 2023 to December 2023. Data were collected from 250 DM patients who had constant and direct access to telecommunication devices. Participants were randomly assigned to two groups: Group A, the intervention group, and Group B, the control group. Patient compliance was assessed using a medication adherence questionnaire, which included questions about physical activity and medical appointments. Results Data were collected from 250 diabetic patients in two groups. The mean age in the intervention group was 55.01 ± 9.81 years and in the control group 57.23 ± 9.25 years. There were 125 participants in each group, and among these, in the intervention group, 48% were male and 52% were female. In the intervention group, HbA1c levels decreased from 8.5 ± 1.2% at baseline to 7.2 ± 1.0% at follow-up, compared to marginal changes in the control group (8.7 ± 1.1% to 8.4 ± 1.0%). In the intervention group, mean scores for physical functioning increased from 65 ± 5 at baseline to 75 ± 6 at follow-up, indicating enhanced functional capacity. Similarly, mental health scores showed improvement, with mean values rising from 70 ± 7 to 75 ± 8. Emotional well-being also demonstrated significant enhancement, with mean scores increasing from 60 ± 6 to 70 ± 7. Conclusion It is concluded that the health intervention implemented in this study significantly improved patient compliance and positively impacted health outcomes in diabetes management. With higher adherence rates to prescribed treatments and substantial improvements in key health metrics, including HbA1c levels, blood pressure, and cholesterol, the intervention demonstrated its efficacy.
引言
糖尿病是全球发病和死亡的主要原因。饮食和药物治疗依从性差在糖尿病患者中很常见，这使得血糖控制难以实现。
目的
评估个性化健康干预对糖尿病（DM）患者治疗依从性和临床结局的影响。
方法
这项准实验研究于2023年1月至2023年12月在卡拉奇的阿迦汗大学医院进行。从250名能持续直接使用电信设备的糖尿病患者中收集数据。参与者被随机分为两组：A组为干预组，B组为对照组。使用药物依从性问卷评估患者的依从性，该问卷包括有关身体活动和医疗预约的问题。
结果
从两组的250名糖尿病患者中收集了数据。干预组的平均年龄为55.01±9.81岁，对照组为57.23±9.25岁。每组有125名参与者，其中干预组中48%为男性，52%为女性。干预组的糖化血红蛋白（HbA1c）水平从基线时的8.5±1.2%降至随访时的7.2±1.0%，而对照组仅有轻微变化（从8.7±1.1%降至8.4±1.0%）。干预组的身体功能平均得分从基线时的65±5提高到随访时的75±6，表明功能能力增强。同样，心理健康得分也有所改善，平均值从70±7提高到75±8。情绪幸福感也显著增强，平均得分从60±6提高到70±7。
结论
得出结论，本研究实施的健康干预显著提高了患者的依从性，并对糖尿病管理的健康结局产生了积极影响。通过对规定治疗的更高依从率以及包括HbA1c水平、血压和胆固醇在内的关键健康指标的大幅改善，该干预证明了其有效性。
