Yokomizo Ryo, Kato Tsuguhiko, Urayama Kevin Y, Nakamura Akari, Sato Makoto, Nasu Risa, Hine Maaya, Kishi Hiroshi, Sago Haruhiko, Okamoto Aikou, Umezawa Akihiro
Center for Regenerative Medicine, National Center for Child Health and Development Research Institute, 2-10-1 Okura, Setagaya-ku, Tokyo, 157-8535, Japan.
Department of Obstetrics and Gynecology, The Jikei University School of Medicine, 3-25-8 Nishi-Shimbashi, Minato-ku, Tokyo, 105-8461, Japan.
Sci Rep. 2025 Jul 1;15(1):21874. doi: 10.1038/s41598-025-08043-w.
In Japan, there is a registry for fertility treatment (the JSOG registry), which is a system that only registers select clinical data related to assisted reproductive technology (ART). This system does not include patient-derived data, so innovative tools that can complement the shortcomings of the existing registry may be useful. In this study we explored the potential of using a smartphone application platform to collect clinical data from patients directly. We recruited participants using the smartphone application “” and requested information that is typically gathered during a medical checkup, including basic physical characteristics, medical history, and results of fertility examinations such as hormone levels and semen analysis. We also asked the participants about the most recent fertility treatment they received and the details of the treatment. We recruited more than 13,000 participants within Japan nationwide in one month, and successfully collected information that is necessary in clinical practice for fertility treatment. Furthermore, through the participants, we were able to obtain information concerning their partners. We gained an expanded understanding of the circumstances surrounding fertility tests performed in Japan and details of fertility treatment such as ovarian stimulation and pregnancy outcomes by each fertility treatment method. This smartphone application has the potential as a promising tool for doctors and couples for information management during fertility treatment.
The online version contains supplementary material available at 10.1038/s41598-025-08043-w.
在日本,有一个生育治疗登记系统(日本生殖医学会登记系统),该系统仅登记与辅助生殖技术(ART)相关的特定临床数据。该系统不包括患者来源的数据,因此能够弥补现有登记系统不足的创新工具可能会很有用。在本研究中,我们探索了使用智能手机应用平台直接从患者收集临床数据的潜力。我们使用智能手机应用程序“ ”招募参与者,并要求提供通常在体检期间收集到的信息,包括基本身体特征、病史以及生育检查结果,如激素水平和精液分析。我们还询问了参与者他们最近接受的生育治疗及其治疗细节。我们在一个月内在日本全国范围内招募了超过13000名参与者,并成功收集了生育治疗临床实践中所需的信息。此外,通过参与者,我们还能够获取有关其伴侣的信息。我们对日本进行的生育测试的相关情况以及每种生育治疗方法的卵巢刺激和妊娠结局等生育治疗细节有了更广泛的了解。这款智能手机应用程序有潜力成为医生和夫妇在生育治疗期间进行信息管理的一个很有前景的工具。
在线版本包含可在10.1038/s41598 - 025 - 08043 - w获取的补充材料。