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药剂师对流感疫苗和肺炎球菌疫苗的接种情况:系统评价与荟萃分析。

Influenza and pneumococcal vaccines uptake among pharmacists: systematic review and meta-analysis.

作者信息

Waszkiewicz Michał, Wnuk Katarzyna, Świtalski Jakub, Augustynowicz Anna

机构信息

School of Public Health, Centre of Postgraduate Medical Education of Warsaw, Warsaw, Poland.

Department of Health Policy Programs, Department of Health Technology Assessment, Agency for Health Technology Assessment and Tariff System, Warsaw, Poland.

出版信息

Commun Med (Lond). 2025 Jul 1;5(1):258. doi: 10.1038/s43856-025-00976-7.

DOI:10.1038/s43856-025-00976-7
PMID:40595446
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12218444/
Abstract

BACKGROUND

Influenza virus and pneumococcal infections are associated with serious health risks resulting from complications. Vaccinations are an effective method of preventing them. Pharmacists can play an essential role in promoting and administering vaccines. High vaccination rates among pharmacists could increase their credibility as vaccination advocates. The review aims to discuss the influenza and pneumococcal vaccination coverage among pharmacists and factors influencing the willingness to vaccinate.

METHODS

The systematic review was performed according to PRISMA guidelines across three medical databases: Medline (via PubMed), Embase (via OVID), and Cochrane Library. The quality assessment of the study was carried out using The Quality Assessment Tool for Observational Cohort and Cross-Sectional Studies. A meta-analysis was also conducted to estimate pharmacists' overall influenza vaccination coverage, incorporating an analysis of vaccination trends before and during the COVID-19 pandemic.

RESULTS

The meta-analysis of 6194 observations and 3585 events reveals an overall influenza vaccination coverage among pharmacists of 50.78% under a random effects model, with a 95% confidence interval ranging from 36.20% to 65.22%. Only one retrieved study analyzes pharmacists' vaccination coverage against pneumococci. According to the findings, 20.8% of the participants in the study were vaccinated against pneumococci.

CONCLUSIONS

The current influenza vaccination rate among pharmacists is moderate, and concerted efforts are needed to increase it. This involves implementing continuous education, beginning at the pharmacy degree stage.

摘要

背景

流感病毒感染和肺炎球菌感染会引发并发症,带来严重的健康风险。接种疫苗是预防这些疾病的有效方法。药剂师在推广和接种疫苗方面可发挥重要作用。药剂师的高接种率可提升他们作为疫苗接种倡导者的可信度。本综述旨在探讨药剂师的流感和肺炎球菌疫苗接种覆盖率以及影响接种意愿的因素。

方法

根据PRISMA指南,在三个医学数据库中进行了系统综述:Medline(通过PubMed)、Embase(通过OVID)和Cochrane图书馆。使用观察性队列研究和横断面研究质量评估工具对研究进行质量评估。还进行了荟萃分析,以估计药剂师的总体流感疫苗接种覆盖率,并分析了2019冠状病毒病大流行之前和期间的接种趋势。

结果

对6194项观察和3585例事件的荟萃分析显示,在随机效应模型下,药剂师的总体流感疫苗接种覆盖率为50.78%,95%置信区间为36.20%至65.22%。检索到的研究中只有一项分析了药剂师的肺炎球菌疫苗接种覆盖率。根据研究结果,该研究中20.8%的参与者接种了肺炎球菌疫苗。

结论

目前药剂师的流感疫苗接种率处于中等水平,需要共同努力提高这一比率。这包括从药学学位阶段开始实施持续教育。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b208/12218444/42959444b5fc/43856_2025_976_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b208/12218444/2db05d5b6cad/43856_2025_976_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b208/12218444/7bdbcc44e174/43856_2025_976_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b208/12218444/e0cc44bd278e/43856_2025_976_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b208/12218444/42959444b5fc/43856_2025_976_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b208/12218444/2db05d5b6cad/43856_2025_976_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b208/12218444/7bdbcc44e174/43856_2025_976_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b208/12218444/e0cc44bd278e/43856_2025_976_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b208/12218444/42959444b5fc/43856_2025_976_Fig4_HTML.jpg

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本文引用的文献

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Hum Vaccin Immunother. 2025 Dec;21(1):2489889. doi: 10.1080/21645515.2025.2489889. Epub 2025 Apr 21.
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Prevention and Control of Seasonal Influenza with Vaccines: Recommendations of the Advisory Committee on Immunization Practices - United States, 2024-25 Influenza Season.疫苗预防和控制季节性流感:免疫实践咨询委员会的建议-美国,2024-25 流感季节。
MMWR Recomm Rep. 2024 Aug 29;73(5):1-25. doi: 10.15585/mmwr.rr7305a1.
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Readiness of and barriers for community pharmacy professionals in providing and implementing vaccination services.
社区药剂师在提供和实施疫苗接种服务方面的准备情况和障碍。
BMC Health Serv Res. 2024 Jul 30;24(1):867. doi: 10.1186/s12913-024-11349-6.
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Impact of the COVID-19 Pandemic on Influenza Vaccination Coverage of Healthcare Personnel in Alicante, Spain.新冠疫情对西班牙阿利坎特医护人员流感疫苗接种覆盖率的影响
Vaccines (Basel). 2024 Apr 1;12(4):370. doi: 10.3390/vaccines12040370.
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Med Sci Monit. 2024 Jan 2;30:e941406. doi: 10.12659/MSM.941406.
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