Naser Nemat Khalid Abd Almajed, Bashir Mazin Babekir Musa, Ali Alhaj Saad Mohamed Ahmed
Department of Microbiology, Faculty of Medical Laboratory Sciences, Shendi University, Shendi Cite, Sudan.
Department of public health- faculty of public health, Shendi University, Shendi City, Sudan.
BMC Gastroenterol. 2025 Jul 1;25(1):466. doi: 10.1186/s12876-025-04074-9.
Helicobacter pylori is a significant pathogen of the gastrointestinal tract infection connected with gastritis, peptic ulcers, and gastric carcinoma. Its infection influences more than half of the world's inhabitants.
This study aimed to investigate the prevalence of H. pylori infection among medical students. Focusing to identify associated risk factors, and provide insights to improve awareness and prevention strategies.
This cross-sectional study was conducted at Shendi University, Sudan, during the period from January to May 2025. The research took place in the Microbiology Laboratory, Faculty of Medical Laboratory Sciences, and included a total of 50 medical students were selected randomly. Data were collected using a structured questionnaire, and H. pylori infection was diagnosed using a fecal antigen test.
Out of the 50 participating students, 18 (36.0%) tested positive for H. pylori infection. The infection was more prevalent among females (46.4%) compared to males (22.7%). The highest infection rate was observed in the 22-23 age group (54.5%). Clinical symptoms such as abdominal pain (p = 0.010) and nausea or vomiting (p = 0.026) were significantly associated with infection. A history of previous diagnosis (p < 0.001) and treatment (p < 0.001) was also strongly correlated with a positive test result. However, no significant associations were found between infection and other factors such as dietary habits, hygiene practices, or smoking.
The findings indicate a relatively high prevalence of H. pylori infection among medical students at Shendi University. These results highlight the need for targeted awareness campaigns and improved preventive strategies within this population.
幽门螺杆菌是一种重要的胃肠道感染病原体，与胃炎、消化性溃疡和胃癌有关。其感染影响着世界上超过一半的人口。
本研究旨在调查医学生中幽门螺杆菌感染的患病率。重点是确定相关危险因素，并提供见解以提高认识和预防策略。
本横断面研究于2025年1月至5月在苏丹的申迪大学进行。研究在医学检验科学学院的微生物实验室进行，共随机选取了50名医学生。使用结构化问卷收集数据，并通过粪便抗原检测诊断幽门螺杆菌感染。
在50名参与研究的学生中，18人（36.0%）幽门螺杆菌感染检测呈阳性。女性感染率（46.4%）高于男性（22.7%）。22 - 23岁年龄组的感染率最高（54.5%）。腹痛（p = 0.010）和恶心或呕吐（p = 0.026）等临床症状与感染显著相关。既往诊断史（p < 0.001）和治疗史（p < 0.001）也与检测结果呈强相关。然而，在感染与饮食习惯、卫生习惯或吸烟等其他因素之间未发现显著关联。
研究结果表明申迪大学医学生中幽门螺杆菌感染率相对较高。这些结果凸显了针对该人群开展有针对性的宣传活动和改进预防策略的必要性。
