由某些蜡样芽孢杆菌的食物、食物中毒及其他临床分离株产生的一种严重坏死性肠毒素。

A severe necrotic enterotoxin produced by certain food, food poisoning and other clinical isolates of Bacillus cereus.

作者信息

Turnbull P C, Nottingham J F, Ghosh A C

出版信息

Br J Exp Pathol. 1977 Jun;58(3):273-80.

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2041137/

Abstract

The ability of certain strains of Bacillus cereus consistently to elaborate a filterable non-dialysable toxin capable of causing severe disruption and necrosis of the intestinal mucosa and submucosa is confirmed. This property is not universal to all B. cereus strains and different degrees of production of this toxin are exhibited by the different strains which produce it. The necrotic effect is produced by whole-cell cultures of the toxin producing strains in broth and in boiled rice. Some characteristics of this necrotic toxin are described and its relationship with the diarrhoeal and other known B. cereus toxins is discussed.

摘要

已证实，某些蜡样芽孢杆菌菌株能够持续产生一种可过滤且不可透析的毒素，该毒素可导致肠黏膜和黏膜下层严重破坏及坏死。这种特性并非所有蜡样芽孢杆菌菌株都具备，产生该毒素的不同菌株表现出不同程度的毒素产生能力。毒素产生菌株的全细胞培养物在肉汤和米饭中均能产生坏死效应。本文描述了这种坏死毒素的一些特性，并讨论了它与腹泻性及其他已知蜡样芽孢杆菌毒素的关系。