鉴定与蜡样芽孢杆菌相关的一种新型肠毒素活性。
Identification of a novel enterotoxigenic activity associated with Bacillus cereus.
作者信息
Melling J, Capel B J, Turnbull P C, Gilbert R J
出版信息
J Clin Pathol. 1976 Oct;29(10):938-40. doi: 10.1136/jcp.29.10.938.
Abstract
A strain of Bacillus cereus isolated from a food poisoning outbreak characterized by vomiting has been shown to be capable of causing vomiting when cultures grown on rice, but not other media, were fed to Rhesus monkeys. In contrast, a strain isolated from a diarrhoeal outbreak produced diarrhoea, but not vomiting, when grown on various media in similar feeding trials. Furthermore, culture filtrates from the diarrhoeal strain caused fluid accumulation in ligated rabbit ileal loops whereas those from the vomiting strain did not. It is proposed that at least two enterotoxins are involved, one responsible for the vomiting and one for the diarrhoeal symptoms.
摘要
从一起以呕吐为特征的食物中毒暴发事件中分离出的一株蜡样芽孢杆菌，已证实当用在米饭上培养而非在其他培养基上培养的菌液喂给恒河猴时，能够引发呕吐。相比之下，从一起腹泻暴发事件中分离出的菌株，在类似的喂食试验中，无论在何种培养基上生长，均会引发腹泻而非呕吐。此外，腹泻菌株的培养滤液会导致结扎的兔回肠肠袢积液，而呕吐菌株的培养滤液则不会。有人提出，至少涉及两种肠毒素，一种导致呕吐，另一种导致腹泻症状。
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