Eriksen Alexander Viktor, Beck Sanne Have, Nielsen Dorthe, Thomsen Katja, Krone Josefine Oredson, Andersen-Ranberg Karen
Geriatric Research Unit, Department of Clinical Research, University of Southern Denmark, Odense, Denmark.
Department of Geriatric Medicine, Odense University Hospital, J.B. Winsløwsvej 4, Odense C, 5000, Denmark.
Trials. 2025 Jul 1;26(1):234. doi: 10.1186/s13063-025-08922-7.
Advancing age is associated with multimorbidity, polypharmacy and functional impairments and older adults with these characteristics are at increased risk of acute admission and readmission. Readmission rate of geriatric patients is high, especially within the first week after discharge. Previous studies on transitional care interventions have mainly showed positive effects, but no study has assessed the effect of a home visit done jointly by a geriatric nurse and a community nurse, with a systematic review of health functions, objective clinical assessment and bedside blood analyses.
A single-centre two-arm parallel group randomised controlled trial using permuted block randomisation will be conducted. Randomisation occurs at discharge. The intervention consists of a follow-up visit within 2-5 days by a geriatric nurse and a community nurse. A systematic review of bodily functions is carried out, and solutions of identified problems are discussed taking into consideration the patient's view. If the patient shows signs of worsened health since discharge vital status and bedside blood analyses using point-of-care-testing (POCT) can be carried out at the discretion of the geriatric nurse. As required the patients will be conferred with a senior geriatrician by video consultation. The patient's primary care physician is invited to participate online. The control group will receive usual discharge. Endpoints are readmission, mortality rates and financial costs. User perspectives include focus group interviews with patients, geriatric nurses, community nurses, geriatricians and primary care physicians.
The intervention is multifactorial to match the needs of complex geriatric patients. We will thus not be able to discern, which part of the intervention has the greatest impact, but the intervention will encompass most of the clinical situation that may potentially lead to acute readmission. If a positive effect is found the intervention may be scaled up to include all departments discharging vulnerable geriatric patients, as well as implemented in guidelines for the discharge of older medical patients.
ClinicalTrials.gov, Identifier: NCT05139823, Registered 1 December 2021.
年龄增长与多种疾病、多种药物治疗及功能障碍相关,具有这些特征的老年人急性入院和再入院风险增加。老年患者的再入院率很高,尤其是在出院后的第一周内。先前关于过渡性护理干预措施的研究主要显示出积极效果,但尚无研究评估老年护士和社区护士联合进行家访,并对健康功能进行系统评估、进行客观临床评估和床边血液分析的效果。
将进行一项单中心双臂平行组随机对照试验,采用置换区组随机化方法。随机分组在出院时进行。干预措施包括老年护士和社区护士在出院后2至5天内进行随访。对身体功能进行系统评估,并结合患者意见讨论已发现问题的解决方案。如果患者出院后健康状况出现恶化迹象,老年护士可酌情进行生命体征检查和使用即时检验(POCT)进行床边血液分析。根据需要,将通过视频会诊为患者安排资深老年病科医生。邀请患者的初级保健医生在线参与。对照组将接受常规出院指导。观察终点为再入院率、死亡率和财务成本。用户观点包括对患者、老年护士、社区护士、老年病科医生和初级保健医生的焦点小组访谈。
该干预措施具有多因素性,以满足复杂老年患者的需求。因此,我们无法确定干预措施的哪一部分影响最大,但该干预措施将涵盖大多数可能导致急性再入院的临床情况。如果发现有积极效果,该干预措施可能会扩大到包括所有收治易发生再入院的老年患者的科室,并纳入老年内科患者出院指南。
ClinicalTrials.gov,标识符:NCT05139823,于2021年12月1日注册。