Gerull G, Mrowinski D, Janssen T, Anft D
Scand Audiol. 1985;14(3):141-50. doi: 10.3109/01050398509045935.
Influences of stimulus polarity on Jewett wave V are rather small when using clicks which produce two or more polarity changes within a short time interval. In order to separate pressure changes towards rarefaction (R) and towards condensation (C) we applied steep single-slope stimuli returning very slowly to baseline. Brainstem responses recorded from 8 human subjects differed markedly for R and C onset. Amplitudes were much higher for R than for C onset. The main C response was double-peaked with the first peak appearing about 0.5 ms earlier and the second, higher one, 1 ms later than the predominant R wave. The transition from single-slope to click stimulation was investigated by combining R and C slopes. For large time intervals, independent responses to either slope were observed. Down to an on/off interval of 1 ms, the on-response predominated. For still shorter intervals an equalization of R and C responses and a graduation towards click responses was found. Using the same stimuli, cochlear microphonics (CM) and compound action potentials (CAP) were recorded from 7 guinea pigs. The CM did not replicate the slow off-motion of the single-slope stimulus, but returned back to baseline after 0.6 ms. The C compared with R latency of the CAP (peak N1) was also delayed by 0.6 ms. This delay, and that of human peak V, may be explained by CAP initiation only by one direction of basilar membrane motion.
当使用在短时间间隔内产生两个或更多极性变化的滴答声时，刺激极性对朱厄特波V的影响相当小。为了区分向稀疏（R）和向压缩（C）的压力变化，我们应用了非常缓慢回到基线的陡峭单斜率刺激。从8名人类受试者记录的脑干反应在R和C起始时明显不同。R起始时的振幅比C起始时高得多。主要的C反应是双峰的，第一个峰比主要的R波早出现约0.5毫秒，第二个更高的峰晚1毫秒出现。通过组合R和C斜率来研究从单斜率刺激到滴答声刺激的转变。对于较大的时间间隔，观察到对任何一个斜率的独立反应。直到开/关间隔为1毫秒，开启反应占主导。对于更短的间隔，发现R和C反应均衡并逐渐向滴答声反应转变。使用相同的刺激，从7只豚鼠记录了耳蜗微音电位（CM）和复合动作电位（CAP）。CM没有复制单斜率刺激的缓慢关闭运动，而是在0.6毫秒后回到基线。与CAP的R潜伏期（峰N1）相比，C潜伏期也延迟了0.6毫秒。这种延迟以及人类峰V的延迟，可能仅由基底膜运动的一个方向引发CAP来解释。
