Wu Siqin, Qin Xiaowen, Jin Zhenjing, Yang Lanlan
The Second Hospital of Jilin University, Changchun, Jilin, China.
Front Immunol. 2025 Jun 17;16:1590902. doi: 10.3389/fimmu.2025.1590902. eCollection 2025.
IgG4-related pancreatitis (IRP) is a form of chronic pancreatitis characterized by the infiltration of IgG4-positive plasma cells, representing a pancreatic manifestation of IgG4-related disease (IgG4-RD). In recent years, with the growing understanding of IgG4-RD, the incidence of IRP has shown an increasing trend. This article provides a comprehensive review of the latest advancements in the epidemiology, etiology, pathogenesis, clinical manifestations, diagnosis, differential diagnosis, and treatment of IRP.
IgG4相关性胰腺炎（IRP）是一种慢性胰腺炎，其特征为IgG4阳性浆细胞浸润，是IgG4相关性疾病（IgG4-RD）的胰腺表现形式。近年来，随着对IgG4-RD认识的不断深入，IRP的发病率呈上升趋势。本文对IRP在流行病学、病因、发病机制、临床表现、诊断、鉴别诊断及治疗方面的最新进展进行全面综述。
