Knaz Asma, Boujneh Soumaya, Ben Radhia Bechir, Krifa Marwa, BenLimem Iteb, Benzarti Wafa, Abdelghani Ahmed
Pneumology Department, Farhat Hached Hospital, Sousse, Tunisia.
Research Laboratory "Heart Lung Interaction (LR14ES05)", University of Sousse, Sousse, Tunisia.
Future Sci OA. 2025 Dec;11(1):2527473. doi: 10.1080/20565623.2025.2527473. Epub 2025 Jul 2.
Congenital pulmonary airway malformation (CPAM) and pulmonary sequestration (PS) are among the most common congenital lung malformations and their association is extremely rare. In exceptional cases, patients with CPAM remain asymptomatic until adulthood. We report the case of a 30-year-old man who was hospitalized in our pneumology department for fever, cough and chest pain. Radiological and histological findings confirmed the coexistence of CPAM and PS. The patient underwent surgical resection and recovered well. This is one of the few reported cases in the literature that describe the uncommon association of CPAM and PS with an infrequent diagnosis in adulthood. Clinicians should consider congenital malformations in the differential diagnosis of recurrent respiratory infections, particularly when they affect the same pulmonary lobe.
先天性肺气道畸形（CPAM）和肺隔离症（PS）是最常见的先天性肺畸形，二者关联极为罕见。在特殊情况下，CPAM患者直到成年都无症状。我们报告一例30岁男性患者，因发热、咳嗽和胸痛入住我院呼吸内科。影像学和组织学检查结果证实CPAM和PS并存。患者接受了手术切除，恢复良好。这是文献中少数报道的CPAM与PS罕见关联且成年期诊断不常见的病例之一。临床医生在复发性呼吸道感染的鉴别诊断中应考虑先天性畸形，尤其是当感染累及同一肺叶时。
